Thermolysin: Difference between revisions

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[[Image:3dnz.jpg|left|200px|thumb|Crystal Structure of Thermolysin [[3dnz]]]]
[[Image:3dnz.jpg|left|200px|thumb|Crystal Structure of Thermolysin [[3dnz]]]]
{{STRUCTURE_3dnz|  PDB=3dnz  | SIZE=300| SCENE=Thermolysin/Cv/1 |right|CAPTION=Thermolysin complex with Ca and Zn ions [[3dnz]] }}
{{STRUCTURE_3dnz|  PDB=3dnz  | SIZE=400| SCENE=Thermolysin/Cv/1 |right|CAPTION=Thermolysin complex with Ca and Zn ions [[3dnz]] }}


[[Thermolysin]] (TML) is a thermostable metalloproteinase enzyme from ''Bacillus thermoproteolyticus''.  It catalyzes the hydrolysis of peptide bonds  containing hydrophobic residues. The images at the left and at the right correspond to one representative Thermolysin ([[3dnz]]).  See [[Metalloproteases]]  and [[Matrix metalloproteinase]] for discussion.
[[Thermolysin]] (TML) is a thermostable metalloproteinase enzyme from ''Bacillus thermoproteolyticus''.  It catalyzes the hydrolysis of peptide bonds  containing hydrophobic residues. The images at the left and at the right correspond to one representative Thermolysin ([[3dnz]]).  See [[Metalloproteases]]  and [[Matrix metalloproteinase]] for discussion.
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== 3D Structures of Thermolysin ==  
== 3D Structures of Thermolysin ==  


''Update June 2011''
''Update December 2011''




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[[3fv4]], [[3fxp]], [[3flf]], [[3fb0]], [[3fcq]], [[3f28]], [[3f2p]] – TML residues 233-548+inhibitor<br />
[[3fv4]], [[3fxp]], [[3flf]], [[3fb0]], [[3fcq]], [[3f28]], [[3f2p]] – TML residues 233-548+inhibitor<br />
[[3fwd]], [[3for]], [[1y3g]], [[1zdp]], [[1z9g]], [[1pes]], [[1pe7]], [[1pe8]], [[1os0]], [[1kto]], [[1ks7]], [[1kro]], [[1kr6]], [[1kkk]], [[1kjo]], [[1kjp]], [[1qf0]], [[1qf1]], [[1qf2]], [[1hyt]], [[1thl]], [[6tmn]], [[7tln]], [[4tln]], [[5tln]], [[1pe5]], [[3ms3]], [[3msa]], [[3msf]], [[3msn]], [[3n21]], [[3nn7]]  – TML+inhibitor<br />
[[3fwd]], [[3for]], [[1y3g]], [[1zdp]], [[1z9g]], [[1pes]], [[1pe7]], [[1pe8]], [[1os0]], [[1kto]], [[1ks7]], [[1kro]], [[1kr6]], [[1kkk]], [[1kjo]], [[1kjp]], [[1qf0]], [[1qf1]], [[1qf2]], [[1hyt]], [[1thl]], [[6tmn]], [[7tln]], [[4tln]], [[5tln]], [[1pe5]], [[3ms3]], [[3msa]], [[3msf]], [[3msn]], [[3n21]], [[3nn7]]  – TML+inhibitor<br />
[[3ssb]] – TML + Impi-α


[[Category:Topic Page]]
[[Category:Topic Page]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel