2c89: Difference between revisions

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[[Image:2c89.png|left|200px]]
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{{STRUCTURE_2c89|  PDB=2c89  |  SCENE=  }}  
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===STRUCTURE OF THE WILD-TYPE C3BOT1 EXOENZYME (FREE STATE, CRYSTAL FORM I)===
===STRUCTURE OF THE WILD-TYPE C3BOT1 EXOENZYME (FREE STATE, CRYSTAL FORM I)===
{{ABSTRACT_PUBMED_18369192}}


 
==Function==
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[[http://www.uniprot.org/uniprot/ARC3_CBDP ARC3_CBDP]] ADP-ribosylates eukaryotic Rho and Rac proteins on an asparagine residue.  
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{{ABSTRACT_PUBMED_18369192}}


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:018369192</ref><ref group="xtra">PMID:012029083</ref><references group="xtra"/>
<ref group="xtra">PMID:018369192</ref><ref group="xtra">PMID:012029083</ref><references group="xtra"/><references/>
[[Category: Clostridium botulinum]]
[[Category: Clostridium botulinum]]
[[Category: Boquet, P.]]
[[Category: Boquet, P.]]
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[[Category: Menez, A.]]
[[Category: Menez, A.]]
[[Category: Stura, E A.]]
[[Category: Stura, E A.]]
[[Category: Artt motif]]
[[Category: Bacterial toxin]]
[[Category: C3 exoenzyme]]
[[Category: Glycosyltransferase]]
[[Category: Transferase]]

Revision as of 02:05, 11 April 2013

Template:STRUCTURE 2c89

STRUCTURE OF THE WILD-TYPE C3BOT1 EXOENZYME (FREE STATE, CRYSTAL FORM I)STRUCTURE OF THE WILD-TYPE C3BOT1 EXOENZYME (FREE STATE, CRYSTAL FORM I)

Template:ABSTRACT PUBMED 18369192

FunctionFunction

[ARC3_CBDP] ADP-ribosylates eukaryotic Rho and Rac proteins on an asparagine residue.

About this StructureAbout this Structure

2c89 is a 4 chain structure with sequence from Clostridium botulinum. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1][xtra 2]

  1. ↑ Menetrey J, Flatau G, Boquet P, Menez A, Stura EA. Structural basis for the NAD-hydrolysis mechanism and the ARTT-loop plasticity of C3 exoenzymes. Protein Sci. 2008 May;17(5):878-86. Epub 2008 Mar 27. PMID:18369192 doi:10.1110/ps.073398508
  2. ↑ Menetrey J, Flatau G, Stura EA, Charbonnier JB, Gas F, Teulon JM, Le Du MH, Boquet P, Menez A. NAD binding induces conformational changes in Rho ADP-ribosylating clostridium botulinum C3 exoenzyme. J Biol Chem. 2002 Aug 23;277(34):30950-7. Epub 2002 May 23. PMID:12029083 doi:10.1074/jbc.M201844200

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