3f1r: Difference between revisions

Revision as of 12:24, 27 March 2013

[FGF20_HUMAN] Neurotrophic factor that regulates central nervous development and function.^[1]

3f1r is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

↑ Kalinina J, Byron SA, Makarenkova HP, Olsen SK, Eliseenkova AV, Larochelle WJ, Dhanabal M, Blais S, Ornitz DM, Day LA, Neubert TA, Pollock PM, Mohammadi M. Homodimerization controls the fibroblast growth factor 9 subfamily's receptor binding and heparan sulfate-dependent diffusion in the extracellular matrix. Mol Cell Biol. 2009 Sep;29(17):4663-78. Epub 2009 Jun 29. PMID:19564416 doi:10.1128/MCB.01780-08

↑ Zhang X, Ibrahimi OA, Olsen SK, Umemori H, Mohammadi M, Ornitz DM. Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. J Biol Chem. 2006 Jun 9;281(23):15694-700. Epub 2006 Apr 4. PMID:16597617 doi:10.1074/jbc.M601252200

@@ Line 1: / Line 1: @@
-[[Image:3f1r.png|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_3f1r", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
 {{STRUCTURE_3f1r|  PDB=3f1r  |  SCENE=  }}
 ===Crystal structure of FGF20 dimer===
+{{ABSTRACT_PUBMED_19564416}}
+==Function==
-<!--
+[[http://www.uniprot.org/uniprot/FGF20_HUMAN FGF20_HUMAN]] Neurotrophic factor that regulates central nervous development and function.<ref>PMID:16597617</ref>
-The line below this paragraph, {{ABSTRACT_PUBMED_19564416}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 19564416 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_19564416}}
 ==About this Structure==
@@ Line 22: / Line 10: @@
 ==Reference==
-<ref group="xtra">PMID:019564416</ref><references group="xtra"/>
+<ref group="xtra">PMID:019564416</ref><references group="xtra"/><references/>
 [[Category: Homo sapiens]]
 [[Category: Kalinina, J.]]
@@ Line 29: / Line 17: @@
 [[Category: Growth factor]]
 [[Category: Hormone]]
-[[Category: Polymorphism]]
 [[Category: Secreted]]