Flagellar filament of bacteria: Difference between revisions
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The structure of a straight R form of the flagellar filament was reported in 2003<ref name="1ucu">PMID: 12904785</ref>, by fitting a crystallographic model of the monomer<ref name="1io1">PMID: 11268201</ref> into an electron cryomicroscopic density map with resolution approaching 4 Å. The resulting full-length R form monomer, [[1ucu]], included terminal alpha helices that were absent in the crystallographic model. | The structure of a straight R form of the flagellar filament was reported in 2003<ref name="1ucu">PMID: 12904785</ref>, by fitting and extending a crystallographic model of the monomer ([[1io1]])<ref name="1io1">PMID: 11268201</ref> into an electron cryomicroscopic density map with resolution approaching 4 Å. The resulting full-length R form monomer, [[1ucu]], included terminal alpha helices that were absent in the crystallographic model. | ||
The structure of a straight L form of the flagellar filament was reported in 2010<ref name="3a5x">Maki-Yonekura, S., K. Yonekura, & K. Namba, 'Conformational change of flagellin for polymorphic supercoiling of the flagellar filament', Nat. Struct. Mol. Biol. 17, 417–422 (2010). [http://dx.doi.org/10.1038/nsmb.1774 doi:10.1038/nsmb.1774]</ref>. The monomer, [[3a5x]], was obtained by fitting the R-form monomer [[1ucu]] into the electron cryomicroscopy density map. | The structure of a straight L form of the flagellar filament was reported in 2010<ref name="3a5x">Maki-Yonekura, S., K. Yonekura, & K. Namba, 'Conformational change of flagellin for polymorphic supercoiling of the flagellar filament', Nat. Struct. Mol. Biol. 17, 417–422 (2010). [http://dx.doi.org/10.1038/nsmb.1774 doi:10.1038/nsmb.1774]</ref>. The monomer, [[3a5x]], was obtained by fitting the R-form monomer [[1ucu]] into the electron cryomicroscopy density map. | ||
<Structure size='450' frame='true' align='right' caption='' scene='Flagellar_filament_of_bacteria/Yale_morph_r_to_l/1' /> | <Structure size='450' frame='true' align='right' caption='' scene='Flagellar_filament_of_bacteria/Yale_morph_r_to_l/1' /> | ||
Below are morphs between the R and L forms of the monomer ([[1ucu]] and [[3a5x]] respectively) and the filaments. Filament models were kindly provided by T. Fujii and K. Namba. | |||
*R to L Monomer Morph (all residues aligned) (<scene name='Flagellar_filament_of_bacteria/Yale_morph_r_to_l/1'> restore initial scene</scene>)<ref>Chemically possible morph generated by the [http://molmovdb.org Yale Morph Server (molmovdb.org)], [[1ucu]] to [[3a5x]].</ref> | *R to L Monomer Morph (all residues aligned) (<scene name='Flagellar_filament_of_bacteria/Yale_morph_r_to_l/1'> restore initial scene</scene>)<ref>Chemically possible morph generated by the [http://molmovdb.org Yale Morph Server (molmovdb.org)], [[1ucu]] to [[3a5x]].</ref> | ||