YbgF: Difference between revisions
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[[Image:YbgF.jpg|300px|left|thumb| The Structure of YbgF<ref name='Gerding'>PMID: 17233825</ref> ]] | [[Image:YbgF.jpg|300px|left|thumb| The Structure of YbgF<ref name='Gerding'>PMID: 17233825</ref> ]] | ||
{{STRUCTURE_2xev| PDB=2xev | SIZE=400| SCENE=YbgF/Ntermygbf/1 |right|CAPTION=Ybgf TPR domain, [[2xev]] }} | |||
{{STRUCTURE_2wz7| PDB=2wz7 | SIZE=400| SCENE=YbgF/Ybgf/1 |right|CAPTION=E. Coli Ybgf N terminal, [[2wz7]] }} | |||
{{STRUCTURE_2xev | PDB=2xev | SCENE= YbgF/Ntermygbf/1 }} | {{STRUCTURE_2xev | PDB=2xev | SCENE= YbgF/Ntermygbf/1 }} | ||
{{STRUCTURE_2wz7 | PDB=2wz7 | SCENE= YbgF/Ybgf/1 }} | {{STRUCTURE_2wz7 | PDB=2wz7 | SCENE= YbgF/Ybgf/1 }} | ||
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Studies have shown that inactivation of the YbgF gene results in no discernible change in the activity of Tol<ref name='Walberger'>PMID: 11994151</ref>. Therefore, replacing the protein with another would not rescue any lost function. Future research may look into comparison of different gram negative bacteria in order to determine if the function is conserved. One particular organism that is known to not have this domain conserved is ''Chlamydiae''<ref name='Krachler'>PMID: 20816983</ref>. Future research may look into the functioning of its Tol system, with a the possible addition of the YbgF domain to study what effect this might have. | Studies have shown that inactivation of the YbgF gene results in no discernible change in the activity of Tol<ref name='Walberger'>PMID: 11994151</ref>. Therefore, replacing the protein with another would not rescue any lost function. Future research may look into comparison of different gram negative bacteria in order to determine if the function is conserved. One particular organism that is known to not have this domain conserved is ''Chlamydiae''<ref name='Krachler'>PMID: 20816983</ref>. Future research may look into the functioning of its Tol system, with a the possible addition of the YbgF domain to study what effect this might have. | ||
==3D structures of Ygbf== | |||
[[2wz7]], [[2xdj]] – Ygbf N terminal – ''Escherichia coli''<br /> | |||
[[2xev]] – Ygbf TPR domain – ''Xanthomonas campestris'' | |||
==References== | ==References== | ||
<references/> | <references/> | ||