Serotonin Transporter: Difference between revisions
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<StructureSection load=' | <StructureSection load='sq6h' size='500' side='right' caption='Structure of the SERT Homologue LeuT, ([[2q6h]]))' scene=''> | ||
[[Serotonin Transporter]]'''s''' ('''SERTs''') are integral membrane proteins that transport serotonin from synaptic spaces into presynaptic neurons. Serotonin is an important neurotransmitter which impacts a mammal’s perception of resource availability, regulates mood, and some cognitive functions like memory and learning. It is also converted into melatonin by [[Serotonin N-acetyltransferase]] to regulate sleep cycles. SERTs function by reuptaking serotonin in the synaptic cleft, effectively terminating the function of serotonin and halting neuronal transmission. Serotonin reuptake is a critical process to prevent overstimulation of nerves.<ref>PMID:10405096</ref> Inappropriately low levels of serotonin, either due to reduced production or overly active SERTs, can cause a number of psychiatric disorders. | [[Serotonin Transporter]]'''s''' ('''SERTs''') are integral membrane proteins that transport serotonin from synaptic spaces into presynaptic neurons. Serotonin is an important neurotransmitter which impacts a mammal’s perception of resource availability, regulates mood, and some cognitive functions like memory and learning. It is also converted into melatonin by [[Serotonin N-acetyltransferase]] to regulate sleep cycles. SERTs function by reuptaking serotonin in the synaptic cleft, effectively terminating the function of serotonin and halting neuronal transmission. Serotonin reuptake is a critical process to prevent overstimulation of nerves.<ref>PMID:10405096</ref> Inappropriately low levels of serotonin, either due to reduced production or overly active SERTs, can cause a number of psychiatric disorders. | ||