Homology modeling servers: Difference between revisions
Eric Martz (talk | contribs) |
Eric Martz (talk | contribs) |
||
| Line 40: | Line 40: | ||
[http://www.sbg.bio.ic.ac.uk/~phyre/ Phyre2] | [http://www.sbg.bio.ic.ac.uk/~phyre/ Phyre2] | ||
</td><td> | </td><td> | ||
For short untemplated regions (e.g. 1-5 untemplated residues), | For short untemplated regions (e.g. 1-5 untemplated residues), the untemplated target residues are present in the 3D model, and registration is maintained according to the sequence alignment by bunching up the untemplated residues in the 3D model, allowing the untemplated target residues to bulge away from the template in the 3D model. | ||
<br><br> | <br><br> | ||
<font color="red">Caution:</font> For long untemplated regions (e.g. 87 residues), the untemplated target residues are omitted from the 3D model, effectively ligating** the templated boundary residues together. The omission fails to reveal, in the 3D model, that a large untemplated region exists. | <font color="red">Caution:</font> For long untemplated regions (e.g. 87 residues), the untemplated target residues are omitted from the 3D model, effectively ligating** the templated boundary residues together. The omission fails to reveal, in the 3D model, that a large untemplated region exists. | ||