Syn and anti nucleosides: Difference between revisions

No edit summary
No edit summary
Line 5: Line 5:
    
    
== Pyrimidine Nucleosides ==
== Pyrimidine Nucleosides ==
<scene name='User:Karl_Oberholser/Sandbox_1/Anti_uridine/1'>View</scene> of uridine in the anti conformation, the oxygen on C-2 of uridine is projecting away from the furanose ring.  <scene name='User:Karl_Oberholser/Sandbox_1/Syn_cytidine/1'>View</scene> of cytidine in the syn conformation, the oxygen on C-2 is projecting toward the furanose ring.  <scene name='User:Karl_Oberholser/Sandbox_1/Syn_cytidine2/4'>View</scene> oxygen at the C-2 position of cytidine invading the space of both hydrogen at C-2' and the oxygen of the furanose ring. Since both pyrimidines found in DNA have an oxygen at the C-2 position, nucleosides and nucleotides of these pyrimidines only adopt the anti conformation and therefore can not be part of Z-DNA.
<scene name='Syn_and_anti_nucleosides/Anti-uridine/1'>View</scene> of uridine in the anti conformation, the oxygen on <font color=orange>C-2</font> of uridine is projecting away from the furanose ring.  <scene name='Syn_and_anti_nucleosides/Syn-cytidine/1'>View</scene> of cytidine in the syn conformation, the oxygen on <font color=orange>C-2</font> is projecting toward the furanose ring.  <scene name='User:Karl_Oberholser/Sandbox_1/Syn_cytidine2/4'>View</scene> oxygen at the C-2 position of cytidine invading the space of both hydrogen at C-2' and the oxygen of the furanose ring. Since both pyrimidines found in DNA have an oxygen at the C-2 position, nucleosides and nucleotides of these pyrimidines only adopt the anti conformation and therefore can not be part of Z-DNA.


== Examples of Nucleotides ==
== Examples of Nucleotides ==

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Karl Oberholser, David Canner, Alexander Berchansky, Angel Herraez