Sandbox Reserved 322: Difference between revisions
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==='''Structure and Function'''=== | ==='''Structure and Function'''=== | ||
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[[Image:Arginine. | [[Image:Arginine.png|thumb|right|300px|Figure 2: General reaction of arginase hydrolyzing L-arginine to urea and L-ornithine adopted from Christianson<ref name="c"/>.]] | ||
In general arginase is a homotrimeric enzyme, which is present in the fifth and final step of the urea cycle for mammals. In humans, hAI converts L-arginine into L-orinithine and urea as shown in figure 2. Human arginase II plays a role in L-arginine homeostasis, by regulating L-arginine concentrations from cellular biosynthetic reactions such as nitric oxide (NO) biosynthesis<ref name="c"/>. Additionally ''Plasmodium falciparum'' arginase is comparable to human arginase, due to the fact that it is 27% identical with human aginase I and II<ref name="b"/>. | In general arginase is a homotrimeric enzyme, which is present in the fifth and final step of the urea cycle for mammals. In humans, hAI converts L-arginine into L-orinithine and urea as shown in figure 2. Human arginase II plays a role in L-arginine homeostasis, by regulating L-arginine concentrations from cellular biosynthetic reactions such as nitric oxide (NO) biosynthesis<ref name="c"/>. Additionally ''Plasmodium falciparum'' arginase is comparable to human arginase, due to the fact that it is 27% identical with human aginase I and II<ref name="b"/>. | ||