Sandbox Reserved 342: Difference between revisions
No edit summary |
No edit summary |
||
| Line 14: | Line 14: | ||
PRTase structures fall into two groups, type I and Type II<ref name="Vos"/>. | PRTase structures fall into two groups, type I and Type II<ref name="Vos"/>. | ||
XGTPase has a conserved sequence,<scene name='Sandbox_Reserved_342/Prib-pp_binding_site/1'>85-IVIDDLVDTG-94</scene>, which is called the PRib-PP (5-phospho-a-D-ribosyl-1-pyrophosphate) binding site<ref name="Vos"/>. This binding site features two adjacent acidic residues, which are surrounded by hydrophobic residues<ref name="Vos"/>. There is a five-stranded b-sheet surrounded by three or four a-helices that creates a conserved structural core containing the PRib-PP binding site<ref name="Vos"/>. Another region of the sequence in XGTPase forms a lobe, which is involved in substrate recognition<ref name="Vos"/>. | XGTPase has a conserved sequence,<scene name='Sandbox_Reserved_342/Prib-pp_binding_site/1'>85-IVIDDLVDTG-94</scene>, which is called the PRib-PP (5-phospho-a-D-ribosyl-1-pyrophosphate) binding site<ref name="Vos"/>. This binding site features two adjacent acidic residues, which are surrounded by hydrophobic residues<ref name="Vos"/>. There is a five-stranded b-sheet surrounded by three or four a-helices that creates a conserved structural core containing the PRib-PP binding site<ref name="Vos"/>. Another region of the sequence in XGTPase forms a lobe, which is involved in substrate recognition<ref name="Vos"/>. | ||
<scene name='Sandbox_Reserved_342/Prib-pp_binding_site/2'>TextToBeDisplayed</scene> | |||
=Function= | =Function= | ||