Sandbox Reserved 165: Difference between revisions
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== Structure == | == Structure == | ||
2HH0 is a crystal structured beta-protein. It has seven strands and a “Greek key” sandwich structure. PDP Protein Data Bank | 2HH0 is a crystal structured beta-protein. It has seven strands and a “Greek key” sandwich structure. 2HH0 is a carrier protein. PDP Protein Data Bank | ||
== Role in Disease == | == Role in Disease == | ||
more | Prion diseases are named differently, depending on which species they affect. In sheep, the disease is called scrapie; in humans, it is called Creutzfeldt-Jakob (named for two German researchers); in deer and elk, it is chronic wasting disease; and in cattle, it is mad cow disease. For reasons that are not clear, prions unfold and create holes in the central nervous system. | ||
Cases of bovine spongioform encephalopathy (BSE), or “mad cow disease,” were identified in 1986 in British cattle. Nine years later, almost half the British herds had been affected and led to the demise of more than 150,000 cattle. This caused the United States and many other countries to refuse blood tranfusions from anyone who had spent more than three months in the United Kingdom from 1986 through 1996. | |||
== References == | == References == | ||
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