Sandbox Reserved 324: Difference between revisions
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=Introduction= | =Introduction= | ||
The translation of proteins requires three steps to occur; initiation, elongation and termination. With each step one or more factors is involved in aiding the process. In eukaryotes initiation has the most factors that are essential for initiation to occur. eIF2 is one of the many initiating factors needed for eukaryotic initiation to occur. It is needed for proper initiation to occur. It initially binds to eIF2β with in the presence of GTP. It then binds to Met-tRNA<sup>meti</sup> and releases the eIF2β. | The translation of proteins requires three steps to occur; initiation, elongation and termination. With each step one or more factors is involved in aiding the process. In eukaryotes initiation has the most factors that are essential for initiation to occur. eIF2 is one of the many initiating factors needed for eukaryotic initiation to occur. It is needed for proper initiation to occur. It initially binds to eIF2β with in the presence of GTP. It then binds to Met-tRNA<sup>meti</sup> and releases the eIF2β. This specific eIF2(1q8k) is the human eIF2 <ref>PMID:15341733</ref>. | ||
{{STRUCTURE_1q8k| PDB=1q8k | SCENE= }} | {{STRUCTURE_1q8k| PDB=1q8k | SCENE= }} | ||
=References= | |||