2gmx: Difference between revisions

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[[Image:2gmx.png|left|200px]]
[[Image:2gmx.png|left|200px]]


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{{STRUCTURE_2gmx|  PDB=2gmx  |  SCENE=  }}  
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===Selective Aminopyridine-Based C-Jun N-terminal Kinase inhibitors with cellular activity===
===Selective Aminopyridine-Based C-Jun N-terminal Kinase inhibitors with cellular activity===


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==See Also==
==See Also==
*[[Mitogen-activated protein kinase]]
*[[Mitogen-activated protein kinase|Mitogen-activated protein kinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:16759099</ref><ref group="xtra">PMID:16527482</ref><references group="xtra"/>
<ref group="xtra">PMID:016759099</ref><ref group="xtra">PMID:016527482</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mitogen-activated protein kinase]]
[[Category: Mitogen-activated protein kinase]]

Revision as of 12:01, 27 July 2012

File:2gmx.png

Template:STRUCTURE 2gmx

Selective Aminopyridine-Based C-Jun N-terminal Kinase inhibitors with cellular activitySelective Aminopyridine-Based C-Jun N-terminal Kinase inhibitors with cellular activity

Template:ABSTRACT PUBMED 16759099

About this StructureAbout this Structure

2gmx is a 4 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1][xtra 2]

  1. Szczepankiewicz BG, Kosogof C, Nelson LT, Liu G, Liu B, Zhao H, Serby MD, Xin Z, Liu M, Gum RJ, Haasch DL, Wang S, Clampit JE, Johnson EF, Lubben TH, Stashko MA, Olejniczak ET, Sun C, Dorwin SA, Haskins K, Abad-Zapatero C, Fry EH, Hutchins CW, Sham HL, Rondinone CM, Trevillyan JM. Aminopyridine-based c-Jun N-terminal kinase inhibitors with cellular activity and minimal cross-kinase activity. J Med Chem. 2006 Jun 15;49(12):3563-80. PMID:16759099 doi:http://dx.doi.org/10.1021/jm060199b
  2. Liu M, Xin Z, Clampit JE, Wang S, Gum RJ, Haasch DL, Trevillyan JM, Abad-Zapatero C, Fry EH, Sham HL, Liu G. Synthesis and SAR of 1,9-dihydro-9-hydroxypyrazolo[3,4-b]quinolin-4-ones as novel, selective c-Jun N-terminal kinase inhibitors. Bioorg Med Chem Lett. 2006 May 15;16(10):2590-4. Epub 2006 Mar 9. PMID:16527482 doi:http://dx.doi.org/10.1016/j.bmcl.2006.02.046

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