Sandbox 80: Difference between revisions
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The chemical formula of <scene name='Sandbox_80/Stickwireframe/1'>Saquinavir</scene> is (C39)(H54)(N6)(O8)S and the molecular weight is 766.94 g/mol.There are 5 aromatic rings, two of which are heterocyclic. One hydroxyl group near the center of the compound that plays an important role in active site binding. The amino groups cause the protease to recognize the drug as a natural substrate with amino acid groups which are recognized by the active sites. | The chemical formula of <scene name='Sandbox_80/Stickwireframe/1'>Saquinavir</scene> is (C39)(H54)(N6)(O8)S and the molecular weight is 766.94 g/mol.There are 5 aromatic rings, two of which are heterocyclic. One hydroxyl group near the center of the compound that plays an important role in active site binding. The amino groups cause the protease to recognize the drug as a natural substrate with amino acid groups which are recognized by the active sites. | ||
==Protein and Drug interations== | ==Protein and Drug interations== | ||
intermolecular forces | intermolecular forces that cause the drug to bind in the active site of the protease are prodominantly H-bonds to | ||
<scene name='Sandbox_80/Hydrophilic/1'>hydrophilic groups</scene> | |||
attraction | attraction | ||