3ptg: Difference between revisions
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{{STRUCTURE_3ptg| PDB=3ptg | SCENE= }} | |||
===Design and Synthesis of a Novel, Orally Efficacious Tri-substituted Thiophene Based JNK Inhibitor=== | |||
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{{ABSTRACT_PUBMED_21316234}} | |||
==About this Structure== | |||
[[3ptg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PTG OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:21316234</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Mitogen-activated protein kinase]] | |||
[[Category: Artis, D R.]] | |||
[[Category: Bard, F.]] | |||
[[Category: Bowers, S.]] | |||
[[Category: Brigham, E F.]] | |||
[[Category: Griswold-Prenner, I.]] | |||
[[Category: Hom, R K.]] | |||
[[Category: Konradi, A W.]] | |||
[[Category: Neitz, J.]] | |||
[[Category: Neitzel, M.]] | |||
[[Category: Pan, H.]] | |||
[[Category: Powell, K.]] | |||
[[Category: Probst, G D.]] | |||
[[Category: Quinn, K P.]] | |||
[[Category: Ruslim, L.]] | |||
[[Category: Sauer, J.]] | |||
[[Category: Sham, H L.]] | |||
[[Category: Toth, G.]] | |||
[[Category: Truong, A P.]] | |||
[[Category: Yao, N.]] | |||
[[Category: Yednock, T A.]] | |||
Revision as of 10:00, 2 March 2011
Design and Synthesis of a Novel, Orally Efficacious Tri-substituted Thiophene Based JNK InhibitorDesign and Synthesis of a Novel, Orally Efficacious Tri-substituted Thiophene Based JNK Inhibitor
Template:ABSTRACT PUBMED 21316234
About this StructureAbout this Structure
3ptg is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Bowers S, Truong AP, Neitz RJ, Neitzel M, Probst GD, Hom RK, Peterson B, Galemmo RA Jr, Konradi AW, Sham HL, Toth G, Pan H, Yao N, Artis DR, Brigham EF, Quinn KP, Sauer JM, Powell K, Ruslim L, Ren Z, Bard F, Yednock TA, Griswold-Prenner I. Design and synthesis of a novel, orally active, brain penetrant, tri-substituted thiophene based JNK inhibitor. Bioorg Med Chem Lett. 2011 Jan 20. PMID:21316234 doi:10.1016/j.bmcl.2011.01.046