1cvl: Difference between revisions
New page: left|200px<br /> <applet load="1cvl" size="450" color="white" frame="true" align="right" spinBox="true" caption="1cvl, resolution 1.6Å" /> '''CRYSTAL STRUCTURE OF... |
No edit summary |
||
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
1CVL is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Chromobacterium_viscosum Chromobacterium viscosum]] with CA as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.3 3.1.1.3]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1CVL OCA]]. | 1CVL is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Chromobacterium_viscosum Chromobacterium viscosum]] with CA as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/Hydrolase Hydrolase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.3 3.1.1.3]]. Structure known Active Sites: ACT, CA and OXY. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1CVL OCA]]. | ||
==Reference== | ==Reference== | ||
| Line 29: | Line 29: | ||
[[Category: x-ray crystallography]] | [[Category: x-ray crystallography]] | ||
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 08:23:26 2007'' | ||
Revision as of 09:18, 30 October 2007
|
CRYSTAL STRUCTURE OF BACTERIAL LIPASE FROM CHROMOBACTERIUM VISCOSUM ATCC 6918
OverviewOverview
The crystal structure of a lipase from the bacterium Chromobacterium, viscosum ATCC 6918 (CVL) has been determined by isomorphous replacement, and refined at 1.6 angstroms resolution to an R-factor of 17.8%. The, lipase has the overall topology of an alpha/beta type protein, which was, also found for previously determined lipase structures. The catalytic, triad of the active center consists of the residues Ser87, Asp263 and, His285. These residues are not exposed to the solvent, but a narrow, channel connects them with the molecular surface. This conformation is, very similar to the previously reported closed conformation of Pseudomonas, glumae lipase (PGL), but superposition of the two lipase structures, reveals several conformational differences. r.m.s. deviations greater than, 2 ... [(full description)]
About this StructureAbout this Structure
1CVL is a [Single protein] structure of sequence from [Chromobacterium viscosum] with CA as [ligand]. Active as [Hydrolase], with EC number [3.1.1.3]. Structure known Active Sites: ACT, CA and OXY. Full crystallographic information is available from [OCA].
ReferenceReference
Crystal structure of a bacterial lipase from Chromobacterium viscosum ATCC 6918 refined at 1.6 angstroms resolution., Lang D, Hofmann B, Haalck L, Hecht HJ, Spener F, Schmid RD, Schomburg D, J Mol Biol. 1996 Jun 21;259(4):704-17. PMID:8683577
Page seeded by OCA on Tue Oct 30 08:23:26 2007