2xp8: Difference between revisions

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m Protected "2xp8" [edit=sysop:move=sysop]
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[[Image:2xp8.jpg|left|200px]]
[[Image:2xp8.png|left|200px]]


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{{STRUCTURE_2xp8|  PDB=2xp8  |  SCENE=  }}  
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===DISCOVERY OF CELL-ACTIVE PHENYL-IMIDAZOLE PIN1 INHIBITORS BY STRUCTURE-GUIDED FRAGMENT EVOLUTION===
===DISCOVERY OF CELL-ACTIVE PHENYL-IMIDAZOLE PIN1 INHIBITORS BY STRUCTURE-GUIDED FRAGMENT EVOLUTION===


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==Reference==
==Reference==
<ref group="xtra">PMID:20932746</ref><references group="xtra"/>
<ref group="xtra">PMID:020932746</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Peptidylprolyl isomerase]]
[[Category: Peptidylprolyl isomerase]]
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[[Category: Scrace, S F.]]
[[Category: Scrace, S F.]]
[[Category: Surgenor, A E.]]
[[Category: Surgenor, A E.]]
[[Category: Cell cycle]]
[[Category: Isomerase]]
[[Category: Oncogenic transformation]]
[[Category: Proline directed kinase]]

Revision as of 22:27, 7 January 2013

File:2xp8.png

Template:STRUCTURE 2xp8

DISCOVERY OF CELL-ACTIVE PHENYL-IMIDAZOLE PIN1 INHIBITORS BY STRUCTURE-GUIDED FRAGMENT EVOLUTIONDISCOVERY OF CELL-ACTIVE PHENYL-IMIDAZOLE PIN1 INHIBITORS BY STRUCTURE-GUIDED FRAGMENT EVOLUTION

Template:ABSTRACT PUBMED 20932746

About this StructureAbout this Structure

2xp8 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Potter A, Oldfield V, Nunns C, Fromont C, Ray S, Northfield CJ, Bryant CJ, Scrace SF, Robinson D, Matossova N, Baker L, Dokurno P, Surgenor AE, Davis B, Richardson CM, Murray JB, Moore JD. Discovery of cell-active phenyl-imidazole Pin1 inhibitors by structure-guided fragment evolution. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6483-8. Epub 2010 Sep 17. PMID:20932746 doi:10.1016/j.bmcl.2010.09.063

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