1z6j: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older editNewer edit →
m Protected "1z6j" [edit=sysop:move=sysop]
No edit summary
Line 1: Line 1:
[[Image:1z6j.png|left|200px]]
[[Image:1z6j.png|left|200px]]


<!--
The line below this paragraph, containing "STRUCTURE_1z6j", creates the "Structure Box" on the page.
You may change the PDB parameter (which sets the PDB file loaded into the applet)
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
or leave the SCENE parameter empty for the default display.
-->
{{STRUCTURE_1z6j|  PDB=1z6j  |  SCENE=  }}  
{{STRUCTURE_1z6j|  PDB=1z6j  |  SCENE=  }}  


===Crystal Structure of a ternary complex of Factor VIIa/Tissue Factor/Pyrazinone Inhibitor===
===Crystal Structure of a ternary complex of Factor VIIa/Tissue Factor/Pyrazinone Inhibitor===


<!--
The line below this paragraph, {{ABSTRACT_PUBMED_15913999}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 15913999 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_15913999}}
{{ABSTRACT_PUBMED_15913999}}


==About this Structure==
==About this Structure==
[[1z6j]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z6J OCA].  
[[1z6j]] is a 3 chain structure of [[Factor VIIa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z6J OCA].  
 
==See Also==
*[[Factor VIIa|Factor VIIa]]


==Reference==
==Reference==
<ref group="xtra">PMID:15913999</ref><ref group="xtra">PMID:12824026</ref><ref group="xtra">PMID:12954057</ref><references group="xtra"/>
<ref group="xtra">PMID:015913999</ref><ref group="xtra">PMID:012824026</ref><ref group="xtra">PMID:012954057</ref><references group="xtra"/>
[[Category: Coagulation factor VIIa]]
[[Category: Coagulation factor VIIa]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]

Revision as of 08:23, 26 July 2012

File:1z6j.png

Template:STRUCTURE 1z6j

Crystal Structure of a ternary complex of Factor VIIa/Tissue Factor/Pyrazinone InhibitorCrystal Structure of a ternary complex of Factor VIIa/Tissue Factor/Pyrazinone Inhibitor

Template:ABSTRACT PUBMED 15913999

About this StructureAbout this Structure

1z6j is a 3 chain structure of Factor VIIa with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1][xtra 2][xtra 3]

  1. ↑ Schweitzer BA, Neumann WL, Rahman HK, Kusturin CL, Sample KR, Poda GI, Kurumbail RG, Stevens AM, Stegeman RA, Stallings WC, South MS. Structure-based design and synthesis of pyrazinones containing novel P1 'side pocket' moieties as inhibitors of TF/VIIa. Bioorg Med Chem Lett. 2005 Jun 15;15(12):3006-11. PMID:15913999 doi:10.1016/j.bmcl.2005.04.037
  2. ↑ South MS, Case BL, Wood RS, Jones DE, Hayes MJ, Girard TJ, Lachance RM, Nicholson NS, Clare M, Stevens AM, Stegeman RA, Stallings WC, Kurumbail RG, Parlow JJ. Structure-based drug design of pyrazinone antithrombotics as selective inhibitors of the tissue factor VIIa complex. Bioorg Med Chem Lett. 2003 Jul 21;13(14):2319-25. PMID:12824026
  3. ↑ Parlow JJ, Dice TA, Lachance RM, Girard TJ, Stevens AM, Stegeman RA, Stallings WC, Kurumbail RG, South MS. Polymer-assisted solution-phase library synthesis and crystal structure of alpha-ketothiazoles as tissue factor VIIa inhibitors. J Med Chem. 2003 Sep 11;46(19):4043-9. PMID:12954057 doi:http://dx.doi.org/10.1021/jm030130t

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=1z6j&oldid=1453993"