2gs7: Difference between revisions
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[[Image:2gs7.png|left|200px]] | [[Image:2gs7.png|left|200px]] | ||
{{STRUCTURE_2gs7| PDB=2gs7 | SCENE= }} | {{STRUCTURE_2gs7| PDB=2gs7 | SCENE= }} | ||
===Crystal Structure of the inactive EGFR kinase domain in complex with AMP-PNP=== | ===Crystal Structure of the inactive EGFR kinase domain in complex with AMP-PNP=== | ||
{{ABSTRACT_PUBMED_16777603}} | {{ABSTRACT_PUBMED_16777603}} | ||
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==See Also== | ==See Also== | ||
*[[Epidermal Growth Factor Receptor]] | *[[Epidermal Growth Factor Receptor|Epidermal Growth Factor Receptor]] | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:016777603</ref><ref group="xtra">PMID:018046415</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
Revision as of 16:37, 25 July 2012
Crystal Structure of the inactive EGFR kinase domain in complex with AMP-PNPCrystal Structure of the inactive EGFR kinase domain in complex with AMP-PNP
Template:ABSTRACT PUBMED 16777603
About this StructureAbout this Structure
2gs7 is a 2 chain structure of Epidermal Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Zhang X, Gureasko J, Shen K, Cole PA, Kuriyan J. An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor. Cell. 2006 Jun 16;125(6):1137-49. PMID:16777603 doi:10.1016/j.cell.2006.05.013
- ↑ Zhang X, Pickin KA, Bose R, Jura N, Cole PA, Kuriyan J. Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface. Nature. 2007 Nov 29;450(7170):741-4. PMID:18046415 doi:nature05998