3fqv: Difference between revisions

Revision as of 20:01, 26 July 2012

3fqv is a 1 chain structure of Dihydrofolate reductase with sequence from Staphylococcus aureus rf122. Full crystallographic information is available from OCA.

↑ Frey KM, Liu J, Lombardo MN, Bolstad DB, Wright DL, Anderson AC. Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistance. J Mol Biol. 2009 Apr 17;387(5):1298-308. Epub 2009 Feb 26. PMID:19249312 doi:10.1016/j.jmb.2009.02.045

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 [[Image:3fqv.png|left|200px]]
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 {{STRUCTURE_3fqv|  PDB=3fqv  |  SCENE=  }}
 ===Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-[3-(3-methoxy-4-phenylphenyl)but-1-ynyl]-6-methylpyrimidine===
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 ==See Also==
-*[[Dihydrofolate reductase]]
+*[[Dihydrofolate reductase|Dihydrofolate reductase]]
 ==Reference==
-<ref group="xtra">PMID:19249312</ref><references group="xtra"/>
+<ref group="xtra">PMID:019249312</ref><references group="xtra"/>
 [[Category: Dihydrofolate reductase]]
 [[Category: Staphylococcus aureus rf122]]