2zgx: Difference between revisions

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m Protected "2zgx" [edit=sysop:move=sysop]
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[[Image:2zgx.png|left|200px]]
[[Image:2zgx.png|left|200px]]


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{{STRUCTURE_2zgx|  PDB=2zgx  |  SCENE=  }}  
{{STRUCTURE_2zgx|  PDB=2zgx  |  SCENE=  }}  


===Thrombin Inhibition===
===Thrombin Inhibition===


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{{ABSTRACT_PUBMED_19520086}}
{{ABSTRACT_PUBMED_19520086}}


==About this Structure==
==About this Structure==
[[2zgx]] is a 3 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZGX OCA].  
[[2zgx]] is a 3 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZGX OCA].  


==See Also==
==See Also==
*[[Hirudin]]
*[[Hirudin|Hirudin]]
*[[Thrombin|Thrombin]]


==Reference==
==Reference==
<ref group="xtra">PMID:19520086</ref><references group="xtra"/>
<ref group="xtra">PMID:019520086</ref><references group="xtra"/>
[[Category: Hirudo medicinalis]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Thrombin]]
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[[Category: Klebe, G.]]
[[Category: Klebe, G.]]
[[Category: Acute phase]]
[[Category: Acute phase]]
[[Category: Blood clotting/hydrolase inhibitor]]
[[Category: Blood clotting]]
[[Category: Blood coagulation]]
[[Category: Blood coagulation]]
[[Category: Calcium]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]
[[Category: Gamma-carboxyglutamic acid]]
[[Category: Gamma-carboxyglutamic acid]]
[[Category: Glycoprotein]]
[[Category: Glycoprotein]]
[[Category: Hydrolase inhibitor]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Kringle]]
[[Category: Kringle]]
[[Category: Pharmaceutical]]
[[Category: Polymorphism]]
[[Category: Protease]]
[[Category: Protease]]
[[Category: Protease inhibitor]]
[[Category: Protease inhibitor]]

Revision as of 20:29, 25 July 2012

File:2zgx.png

Template:STRUCTURE 2zgx

Thrombin InhibitionThrombin Inhibition

Template:ABSTRACT PUBMED 19520086

About this StructureAbout this Structure

2zgx is a 3 chain structure of Hirudin and Thrombin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. ↑ Baum B, Muley L, Heine A, Smolinski M, Hangauer D, Klebe G. Think twice: understanding the high potency of bis(phenyl)methane inhibitors of thrombin. J Mol Biol. 2009 Aug 21;391(3):552-64. Epub 2009 Jun 9. PMID:19520086 doi:10.1016/j.jmb.2009.06.016

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