Human Cardiac Troponin C: Difference between revisions
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[[Image:EGC-TnC2.jpg|300px|left|thumb|Figure 1: EGCg-TnC complex]] | [[Image:EGC-TnC2.jpg|300px|left|thumb|Figure 1: EGCg-TnC complex]] | ||
[[Image:Pocket surface.jpg|300px| | [[Image:Pocket surface.jpg|300px|left|thumb|Figure 2: Pocket with a surface representation]] | ||
As said just before, EGCg makes contacts exclusively to hydrophobic residues that line the surface of TnC. Actually it binds near the surface of helix E, so near the N-terminus of TnC, with tetrahydropyran and benzenediol. The pyrogallol ring stays near the C-terminus of TnC, which explains the large chemical shift perturbations of some residues of the <scene name='Human_Cardiac_Troponin_C/Helix_h/1'>Helix H</scene>. | As said just before, EGCg makes contacts exclusively to hydrophobic residues that line the surface of TnC. Actually it binds near the surface of helix E, so near the N-terminus of TnC, with tetrahydropyran and benzenediol. The pyrogallol ring stays near the C-terminus of TnC, which explains the large chemical shift perturbations of some residues of the <scene name='Human_Cardiac_Troponin_C/Helix_h/1'>Helix H</scene>. | ||