NodS: Difference between revisions

New page: NodS is a bacterial methyltransferase involved in the pathway leading to the biosynthesis of Nod factor, an important signaling molecule released by rhizobial bacteria in the course of end...
 
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NodS is a bacterial methyltransferase involved in the pathway leading to the biosynthesis of Nod factor, an important signaling molecule released by rhizobial bacteria in the course of endosymbiotic interaction with legumes. NodS from ''Bradyrhizobium japonicum'' WM9 is the first S-adenosyl-L-methionine-dependent methyltransferase specific for chitooligosaccharide substrates, the structure of which has been solved, with ([[3ofk]]) and without ([[3ofj]]) S-adenosyl-L-homocysteine ligand, which is chemically very similar to the methyl donor used by NodS, S-adenosyl-L-methionine.<ref>PMID:19052372</ref><ref>PMID: 20970431</ref>
NodS is a bacterial methyltransferase involved in the pathway leading to the biosynthesis of Nod factor, an important signaling molecule released by rhizobial bacteria in the course of endosymbiotic interaction with legumes. NodS from ''Bradyrhizobium japonicum'' WM9 is the first S-adenosyl-L-methionine-dependent methyltransferase specific for chitooligosaccharide substrates, the structure of which has been solved. The structures with ([[3ofk]]) and without ([[3ofj]]) S-adenosyl-L-homocysteine ligand, which is chemically very similar to the methyl donor used by NodS, S-adenosyl-L-methionine, are available.<ref>PMID:19052372</ref><ref>PMID: 20970431</ref>


==Biological significance==
==Biological significance==

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Marcin Jozef Suskiewicz, David Canner, Michal Harel, Alexander Berchansky