AZT-resistant HIV-1 reverse transcriptase: Difference between revisions
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[[Reverse transcriptase]] is essential to the function of [[HIV]]. In allowing viral RNA to serve as a template for creating double-stranded [[DNA]], [[reverse transcriptase]] greatly contributes to the deadliness of this virus. | [[Reverse transcriptase]] is essential to the function of [[HIV]]. In allowing viral RNA to serve as a template for creating double-stranded [[DNA]], [[reverse transcriptase]] greatly contributes to the deadliness of this virus. | ||
{{STRUCTURE_3klg | PDB=3klg | SCENE= }} | |||
==Structure of Reverse Transcriptase== | ==Structure of Reverse Transcriptase== | ||
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==Reference== | ==Reference== | ||
Sarafianos et al. "Structure and Function of HIV-1 Reverse Transcriptase: Molecular Mechanisms of Polymerization and Inhibition". ''Journal of Molecular Biology'' Volume 385, Issue 3. 23 January 2009. 693-713 | Sarafianos et al. "Structure and Function of HIV-1 Reverse Transcriptase: Molecular Mechanisms of Polymerization and Inhibition". ''Journal of Molecular Biology'' Volume 385, Issue 3. 23 January 2009. 693-713 | ||