3kec: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[3kec]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KEC OCA]. | |||
==Reference== | ==Reference== | ||
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[[Category: Schnute, M E.]] | [[Category: Schnute, M E.]] | ||
[[Category: Shieh, H S.]] | [[Category: Shieh, H S.]] | ||
Revision as of 07:48, 16 February 2011
Crystal Structure of Human MMP-13 complexed with a phenyl-2H-tetrazole compoundCrystal Structure of Human MMP-13 complexed with a phenyl-2H-tetrazole compound
Template:ABSTRACT PUBMED 20005097
About this StructureAbout this Structure
3kec is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Schnute ME, O'Brien PM, Nahra J, Morris M, Howard Roark W, Hanau CE, Ruminski PG, Scholten JA, Fletcher TR, Hamper BC, Carroll JN, Patt WC, Shieh HS, Collins B, Pavlovsky AG, Palmquist KE, Aston KW, Hitchcock J, Rogers MD, McDonald J, Johnson AR, Munie GE, Wittwer AJ, Man CF, Settle SL, Nemirovskiy O, Vickery LE, Agawal A, Dyer RD, Sunyer T. Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis. Bioorg Med Chem Lett. 2010 Jan 15;20(2):576-80. Epub 2009 Nov 22. PMID:20005097 doi:10.1016/j.bmcl.2009.11.081