3o56: Difference between revisions

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'''Unreleased structure'''
[[Image:3o56.jpg|left|200px]]


The entry 3o56 is ON HOLD until Jul 28 2012
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{{STRUCTURE_3o56|  PDB=3o56  |  SCENE=  }}


Authors: Somers, D.O., Neu, M.
===Catalytic domain of human phosphodiesterase 4b2b in complex with a 5-heterocycle pyrazolopyridine inhibitor===


Description: Catalytic domain of human phosphodiesterase 4b2b in complex with a 5-heterocycle pyrazolopyridine inhibitor


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 15 10:35:17 2010''
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{{ABSTRACT_PUBMED_20732811}}
 
==About this Structure==
[[3o56]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O56 OCA].
 
==Reference==
<ref group="xtra">PMID:020732811</ref><references group="xtra"/>
[[Category: 3',5'-cyclic-nucleotide phosphodiesterase]]
[[Category: Homo sapiens]]
[[Category: Neu, M.]]
[[Category: Somers, D O.]]
[[Category: Camp binding]]
[[Category: Hydrolase]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Pde]]
[[Category: Phosphodiesterase]]

Revision as of 11:46, 3 August 2011

File:3o56.jpg

Template:STRUCTURE 3o56

Catalytic domain of human phosphodiesterase 4b2b in complex with a 5-heterocycle pyrazolopyridine inhibitorCatalytic domain of human phosphodiesterase 4b2b in complex with a 5-heterocycle pyrazolopyridine inhibitor

Template:ABSTRACT PUBMED 20732811

About this StructureAbout this Structure

3o56 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Mitchell CJ, Ballantine SP, Coe DM, Cook CM, Delves CJ, Dowle MD, Edlin CD, Hamblin JN, Holman S, Johnson MR, Jones PS, Keeling SE, Kranz M, Lindvall M, Lucas FS, Neu M, Solanke YE, Somers DO, Trivedi NA, Wiseman JO. Pyrazolopyridines as potent PDE4B inhibitors: 5-heterocycle SAR. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5803-6. Epub 2010 Aug 5. PMID:20732811 doi:10.1016/j.bmcl.2010.07.136

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