3ns2: Difference between revisions
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{{STRUCTURE_3ns2| PDB=3ns2 | SCENE= }} | {{STRUCTURE_3ns2| PDB=3ns2 | SCENE= }} | ||
===High-resolution structure of pyrabactin-bound PYL2=== | ===High-resolution structure of pyrabactin-bound PYL2=== | ||
{{ABSTRACT_PUBMED_20630864}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/PYL2_ARATH PYL2_ARATH]] Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA.<ref>PMID:19898420</ref> <ref>PMID:19893533</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3ns2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NS2 OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020630864</ref><references group="xtra"/><references/> | ||
[[Category: Arabidopsis thaliana]] | [[Category: Arabidopsis thaliana]] | ||
[[Category: Hao, Q.]] | [[Category: Hao, Q.]] | ||
| Line 36: | Line 23: | ||
[[Category: Pyl2]] | [[Category: Pyl2]] | ||
[[Category: Pyrabactin]] | [[Category: Pyrabactin]] | ||
Revision as of 14:39, 24 April 2013
High-resolution structure of pyrabactin-bound PYL2High-resolution structure of pyrabactin-bound PYL2
Template:ABSTRACT PUBMED 20630864
FunctionFunction
[PYL2_ARATH] Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA.[1] [2]
About this StructureAbout this Structure
3ns2 is a 3 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Yuan X, Yin P, Hao Q, Yan C, Wang J, Yan N. Single Amino Acid Alteration between Valine and Isoleucine Determines the Distinct Pyrabactin Selectivity by PYL1 and PYL2. J Biol Chem. 2010 Sep 10;285(37):28953-8. Epub 2010 Jul 14. PMID:20630864 doi:10.1074/jbc.M110.160192
- ↑ Melcher K, Ng LM, Zhou XE, Soon FF, Xu Y, Suino-Powell KM, Park SY, Weiner JJ, Fujii H, Chinnusamy V, Kovach A, Li J, Wang Y, Li J, Peterson FC, Jensen DR, Yong EL, Volkman BF, Cutler SR, Zhu JK, Xu HE. A gate-latch-lock mechanism for hormone signalling by abscisic acid receptors. Nature. 2009 Dec 3;462(7273):602-8. PMID:19898420 doi:10.1038/nature08613
- ↑ Yin P, Fan H, Hao Q, Yuan X, Wu D, Pang Y, Yan C, Li W, Wang J, Yan N. Structural insights into the mechanism of abscisic acid signaling by PYL proteins. Nat Struct Mol Biol. 2009 Dec;16(12):1230-6. Epub 2009 Nov 5. PMID:19893533 doi:10.1038/nsmb.1730