Telomerase 3D structures: Difference between revisions
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[[Image:Tert.png|left|200px|thumb|Structure of the catalytic subunit of telomerase, TERT, [[3du5]]]] | [[Image:Tert.png|left|200px|thumb|Structure of the catalytic subunit of telomerase, TERT, [[3du5]]]] | ||
{{STRUCTURE_3du5| PDB=3du5 | SIZE=300| SCENE= |right|CAPTION=Catalytic subunit of telomerase, TERT, [[3du5]] }} | {{STRUCTURE_3du5| PDB=3du5 | SIZE=300| SCENE=Telomerase/Cv/1 |right|CAPTION=Catalytic subunit of telomerase, TERT, [[3du5]] }} | ||
[[Telomerase]] (TEL) adds DNA repeats to the tail end of telomeres. It carries its own RNA. The human TEL is composed of 2 Telomerase Reverse Transcriptase (TERT), 2 Telomerase RNA (TERC) and 2 dyskerin (DKC1) molecules. The images at the left and at the right correspond to one representative Telomerase structure, ''i.e.'' crystal structure of catalytic subunit of telomerase, TERT, from ''Tribolium castaneum'' ([[3du5]]). | [[Telomerase]] (TEL) adds DNA repeats to the tail end of telomeres. It carries its own RNA. The human TEL is composed of 2 Telomerase Reverse Transcriptase (TERT), 2 Telomerase RNA (TERC) and 2 dyskerin (DKC1) molecules. The images at the left and at the right correspond to one representative Telomerase structure, ''i.e.'' crystal structure of catalytic subunit of telomerase, TERT, from ''Tribolium castaneum'' ([[3du5]]). | ||
Revision as of 11:34, 5 August 2010
Telomerase (TEL) adds DNA repeats to the tail end of telomeres. It carries its own RNA. The human TEL is composed of 2 Telomerase Reverse Transcriptase (TERT), 2 Telomerase RNA (TERC) and 2 dyskerin (DKC1) molecules. The images at the left and at the right correspond to one representative Telomerase structure, i.e. crystal structure of catalytic subunit of telomerase, TERT, from Tribolium castaneum (3du5).
3D Structures of Telomerase3D Structures of Telomerase
3du5, 3du6 – Tribolium castaneum
3kyl – TERT+DNA – Tribolium castaneum
2r4g – TtTERT RNA binding domain+RNA – Tetrahymena thermophila
2b2a – TtTERT (mutant)