3n00: Difference between revisions

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[[Image:3n00.png|left|200px]]
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{{STRUCTURE_3n00|  PDB=3n00  |  SCENE=  }}  
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===Crystal Structure of a deletion mutant of human Reverba ligand binding domain bound with an NCoR ID1 peptide determined to 2.60A===
===Crystal Structure of a deletion mutant of human Reverba ligand binding domain bound with an NCoR ID1 peptide determined to 2.60A===
{{ABSTRACT_PUBMED_20581824}}


 
==Function==
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[[http://www.uniprot.org/uniprot/NR1D1_HUMAN NR1D1_HUMAN]] Functions as a constitutive transcriptional repressor. In collaboration with SP1, activates GJA1 transcription (By similarity). Possible receptor for triiodothyronine.<ref>PMID:2539258</ref> <ref>PMID:1971514</ref>  [[http://www.uniprot.org/uniprot/NCOR1_HUMAN NCOR1_HUMAN]] Mediates transcriptional repression by certain nuclear receptors. Part of a complex which promotes histone deacetylation and the formation of repressive chromatin structures which may impede the access of basal transcription factors.<ref>PMID:14527417</ref>
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{{ABSTRACT_PUBMED_20581824}}


==About this Structure==
==About this Structure==
3N00 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N00 OCA].  
[[3n00]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N00 OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:20581824</ref><references group="xtra"/>
<ref group="xtra">PMID:020581824</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Gampe, R.]]
[[Category: Gampe, R.]]
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[[Category: Reverba ncorid1]]
[[Category: Reverba ncorid1]]
[[Category: Transcription regulator]]
[[Category: Transcription regulator]]
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