User:Daniel Seeman/DELETE: Difference between revisions
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=== Forms of Caspase-7 === | === Forms of Caspase-7 === | ||
*<scene name='User:Daniel_Seeman/Caspase-7_Dynamics/1f1j/1'>Caspase-7 bound to dead-end substrate mimic DEVD-CHO</scene>, trapping protein in active/substrate bound conformation. | *<scene name='User:Daniel_Seeman/Caspase-7_Dynamics/1f1j/1'>Caspase-7 bound to dead-end substrate mimic DEVD-CHO</scene>, trapping protein in active/substrate bound conformation. | ||
*<scene name='User:Daniel_Seeman/Caspase-7_Dynamics/1shj-234234/1'>Caspase-7 bound to allosteric inhibitor DICA through CYS290</scene> trapping protein in a form incompatible with substrate binding. | |||
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Molecular Playground banner: Conformational Dynamics between active and allosterically inhibited caspase-7 elucidate the mechanism of allostery in this important class of cysteine proteases. | Molecular Playground banner: Conformational Dynamics between active and allosterically inhibited caspase-7 elucidate the mechanism of allostery in this important class of cysteine proteases. | ||