User talk:Johan sunryd/sandbox 1: Difference between revisions
Johan Sunryd (talk | contribs) Molecular Playground/ERMan1 |
Johan Sunryd (talk | contribs) Molecular Playground/ ER mannosidases 1 |
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Alpha-mannosidases I is a human protein that reside in the endoplasmic reticulum(ER) lumen. ERMan1 is part of the class 1 glycosylhydrolase family 47 group of proteins and sports a Tim-barrel fold. In the ER N-linked glycans are used as indicators of how well a client protein is folded. ERMan1 functions by slowly trimming N-linked glycans, giving the protein at hand a defined window of time before the client protein can be targeted for degradation by other ER proteins. | Alpha-mannosidases I(ERMan1) is a human protein that reside in the endoplasmic reticulum(ER) lumen. ERMan1 is part of the class 1 glycosylhydrolase family 47 group of proteins and sports a Tim-barrel fold. In the ER N-linked glycans are used as indicators of how well a client protein is folded. ERMan1 functions by slowly trimming N-linked glycans, giving the protein at hand a defined window of time before the client protein can be targeted for degradation by other ER proteins. | ||
{{Clear}} | {{Clear}} | ||
<applet load='1X9D' size='[450,338]' frame='true' align='right' | <applet load='1X9D' size='[450,338]' frame='true' align='right' | ||
caption='ERMan1 (1X9D)' scene=' | caption='ERMan1 (1X9D)' <scene name='User_talk:Johan_sunryd/sandbox_1/Catalytic_site_of_erman_1/1'>TextToBeDisplayed</scene> | ||
=== Catalytic Site === | === Catalytic Site === | ||
Latest revision as of 05:07, 30 April 2010
Alpha-mannosidases I(ERMan1) is a human protein that reside in the endoplasmic reticulum(ER) lumen. ERMan1 is part of the class 1 glycosylhydrolase family 47 group of proteins and sports a Tim-barrel fold. In the ER N-linked glycans are used as indicators of how well a client protein is folded. ERMan1 functions by slowly trimming N-linked glycans, giving the protein at hand a defined window of time before the client protein can be targeted for degradation by other ER proteins.
<applet load='1X9D' size='[450,338]' frame='true' align='right' caption='ERMan1 (1X9D)' <scene name='User_talk:Johan_sunryd/sandbox_1/Catalytic_site_of_erman_1/1'>TextToBeDisplayed</scene>
Catalytic SiteCatalytic Site
The spinning protein () ) is a highlight of the catalytic residues of ERMan1.
"Molecular Playground banner: A catalytic timer for protein degradation."