2x6e: Difference between revisions

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'''Unreleased structure'''
{{Seed}}
[[Image:2x6e.jpg|left|200px]]


The entry 2x6e is ON HOLD until Paper Publication
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{{STRUCTURE_2x6e|  PDB=2x6e  |  SCENE=  }}


Authors: Kosmopoulou, M., Bayliss, R.
===AURORA-A BOUND TO AN INHIBITOR===


Description: Aurora-A bound to an inhibitor


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{{ABSTRACT_PUBMED_20565112}}
 
==About this Structure==
2X6E is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X6E OCA].
 
==Reference==
<ref group="xtra">PMID:20565112</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Bayliss, R.]]
[[Category: Kosmopoulou, M.]]
[[Category: Cell cycle]]
[[Category: Mitosis]]
[[Category: Transferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul  7 08:38:33 2010''

Revision as of 07:32, 7 July 2010

File:2x6e.jpg

Template:STRUCTURE 2x6e

AURORA-A BOUND TO AN INHIBITORAURORA-A BOUND TO AN INHIBITOR

Template:ABSTRACT PUBMED 20565112

About this StructureAbout this Structure

2X6E is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Bavetsias V, Large JM, Sun C, Bouloc N, Kosmopoulou M, Matteucci M, Wilsher NE, Martins V, Reynisson J, Atrash B, Faisal A, Urban F, Valenti M, de Haven Brandon A, Box G, Raynaud FI, Workman P, Eccles SA, Bayliss R, Blagg J, Linardopoulos S, McDonald E. Imidazo[4,5-b]pyridine Derivatives As Inhibitors of Aurora Kinases: Lead Optimization Studies toward the Identification of an Orally Bioavailable Preclinical Development Candidate. J Med Chem. 2010 Jun 21. PMID:20565112 doi:10.1021/jm100262j

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