3k0f: Difference between revisions

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[[Image:3k0f.jpg|left|200px]]
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{{STRUCTURE_3k0f|  PDB=3k0f  |  SCENE=  }}  
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===Crystal structure of the phosphorylation-site double mutant T426A/T432A of the KaiC circadian clock protein===
===Crystal structure of the phosphorylation-site double mutant T426A/T432A of the KaiC circadian clock protein===
{{ABSTRACT_PUBMED_19956664}}


==Function==
[[http://www.uniprot.org/uniprot/KAIC_SYNE7 KAIC_SYNE7]] Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction.<ref>PMID:9727980</ref><ref>PMID:14709675</ref>


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==About this Structure==
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[[3k0f]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Synechococcus_elongatus_pcc_7942 Synechococcus elongatus pcc 7942]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K0F OCA].
(as it appears on PubMed at http://www.pubmed.gov), where 19956664 is the PubMed ID number.
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{{ABSTRACT_PUBMED_19956664}}


==About this Structure==
==See Also==
3K0F is a 6 chains structure with sequences from [http://en.wikipedia.org/wiki/Synechococcus_elongatus_pcc_7942 Synechococcus elongatus pcc 7942]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K0F OCA].
*[[Circadian clock protein|Circadian clock protein]]


==Reference==
==Reference==
<ref group="xtra">PMID:19956664</ref><references group="xtra"/>
<ref group="xtra">PMID:019956664</ref><references group="xtra"/><references/>
[[Category: Calcium/calmodulin-dependent protein kinase]]
[[Category: Calcium/calmodulin-dependent protein kinase]]
[[Category: Synechococcus elongatus pcc 7942]]
[[Category: Synechococcus elongatus pcc 7942]]
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[[Category: Transcription regulation]]
[[Category: Transcription regulation]]
[[Category: Transferase]]
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 31 13:34:39 2010''

Revision as of 12:12, 27 March 2013

Template:STRUCTURE 3k0f

Crystal structure of the phosphorylation-site double mutant T426A/T432A of the KaiC circadian clock proteinCrystal structure of the phosphorylation-site double mutant T426A/T432A of the KaiC circadian clock protein

Template:ABSTRACT PUBMED 19956664

FunctionFunction

[KAIC_SYNE7] Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction.[1][2]

About this StructureAbout this Structure

3k0f is a 6 chain structure with sequence from Synechococcus elongatus pcc 7942. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. ↑ Pattanayek R, Mori T, Xu Y, Pattanayek S, Johnson CH, Egli M. Structures of KaiC circadian clock mutant proteins: a new phosphorylation site at T426 and mechanisms of kinase, ATPase and phosphatase. PLoS One. 2009 Nov 26;4(11):e7529. PMID:19956664 doi:10.1371/journal.pone.0007529
  1. ↑ Ishiura M, Kutsuna S, Aoki S, Iwasaki H, Andersson CR, Tanabe A, Golden SS, Johnson CH, Kondo T. Expression of a gene cluster kaiABC as a circadian feedback process in cyanobacteria. Science. 1998 Sep 4;281(5382):1519-23. PMID:9727980
  2. ↑ Nakahira Y, Katayama M, Miyashita H, Kutsuna S, Iwasaki H, Oyama T, Kondo T. Global gene repression by KaiC as a master process of prokaryotic circadian system. Proc Natl Acad Sci U S A. 2004 Jan 20;101(3):881-5. Epub 2004 Jan 6. PMID:14709675 doi:10.1073/pnas.0307411100

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