3lkx: Difference between revisions

No edit summary
No edit summary
Line 1: Line 1:
{{Seed}}
[[Image:3lkx.jpg|left|200px]]
<!--
The line below this paragraph, containing "STRUCTURE_3lkx", creates the "Structure Box" on the page.
You may change the PDB parameter (which sets the PDB file loaded into the applet)
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
or leave the SCENE parameter empty for the default display.
-->
{{STRUCTURE_3lkx|  PDB=3lkx  |  SCENE=  }}  
{{STRUCTURE_3lkx|  PDB=3lkx  |  SCENE=  }}  
===Human nac dimerization domain===
===Human nac dimerization domain===
{{ABSTRACT_PUBMED_20214399}}


 
==Function==
<!--
[[http://www.uniprot.org/uniprot/BTF3_HUMAN BTF3_HUMAN]] General transcription factor. BTF3 can form a stable complex with RNA polymerase II. Required for the initiation of transcription. [[http://www.uniprot.org/uniprot/NACA_HUMAN NACA_HUMAN]] Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites). May act as a specific coactivator for JUN, binding to DNA and stabilizing the interaction of JUN homodimers with target gene promoters.<ref>PMID:9877153</ref> <ref>PMID:10982809</ref> <ref>PMID:15784678</ref>
The line below this paragraph, {{ABSTRACT_PUBMED_20214399}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 20214399 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_20214399}}


==About this Structure==
==About this Structure==
3LKX is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LKX OCA].  
[[3lkx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LKX OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:20214399</ref><references group="xtra"/>
<ref group="xtra">PMID:020214399</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hu, Y.]]
[[Category: Hu, Y.]]
Line 32: Line 19:
[[Category: Beta-barrel]]
[[Category: Beta-barrel]]
[[Category: Chaperone]]
[[Category: Chaperone]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 24 08:53:16 2010''

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA