3lpb: Difference between revisions

Revision as of 10:45, 28 April 2010

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:3lpb.jpg

Template:STRUCTURE 3lpb

Crystal structure of Jak2 complexed with a potent 2,8-diaryl-quinoxaline inhibitorCrystal structure of Jak2 complexed with a potent 2,8-diaryl-quinoxaline inhibitor

Template:ABSTRACT PUBMED 20231096

About this StructureAbout this Structure

3LPB is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}

↑ Pissot-Soldermann C, Gerspacher M, Furet P, Gaul C, Holzer P, McCarthy C, Radimerski T, Regnier CH, Baffert F, Drueckes P, Tavares GA, Vangrevelinghe E, Blasco F, Ottaviani G, Ossola F, Scesa J, Reetz J. Discovery and SAR of potent, orally available 2,8-diaryl-quinoxalines as a new class of JAK2 inhibitors. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2609-13. Epub 2010 Feb 19. PMID:20231096 doi:10.1016/j.bmcl.2010.02.056

Page seeded by OCA on Wed Apr 28 10:45:42 2010

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

[1] Pissot-Soldermann C, Gerspacher M, Furet P, Gaul C, Holzer P, McCarthy C, Radimerski T, Regnier CH, Baffert F, Drueckes P, Tavares GA, Vangrevelinghe E, Blasco F, Ottaviani G, Ossola F, Scesa J, Reetz J. Discovery and SAR of potent, orally available 2,8-diaryl-quinoxalines as a new class of JAK2 inhibitors. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2609-13. Epub 2010 Feb 19. PMID:20231096 doi:10.1016/j.bmcl.2010.02.056

[xtra 1]

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{Seed}}
+[[Image:3lpb.jpg|left|200px]]
-The entry 3lpb is ON HOLD  until Paper Publication
+<!--
+The line below this paragraph, containing "STRUCTURE_3lpb", creates the "Structure Box" on the page.
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+or leave the SCENE parameter empty for the default display.
+-->
+{{STRUCTURE_3lpb|  PDB=3lpb  |  SCENE=  }}
-Authors: Tavares, G.A., Pissot-Soldermann, C., Gerspacher, M., Furet, P., Kroemer, M.
+===Crystal structure of Jak2 complexed with a potent 2,8-diaryl-quinoxaline inhibitor===
-Description: Crystal structure of Jak2 complexed with a potent 2,8-diaryl-quinoxaline inhibitor
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 10 13:13:41 2010''
+<!--
+The line below this paragraph, {{ABSTRACT_PUBMED_20231096}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 20231096 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_20231096}}
+==About this Structure==
+LPB is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LPB OCA].
+==Reference==
+<ref group="xtra">PMID:20231096</ref><references group="xtra"/>
+[[Category: Homo sapiens]]
+[[Category: Non-specific protein-tyrosine kinase]]
+[[Category: Furet, P.]]
+[[Category: Gerspacher, M.]]
+[[Category: Kroemer, M.]]
+[[Category: Pissot-Soldermann, C.]]
+[[Category: Tavares, G A.]]
+[[Category: Atp site kinase inhibitor]]
+[[Category: Atp-binding]]
+[[Category: Chromosomal rearrangement]]
+[[Category: Disease mutation]]
+[[Category: Kinase]]
+[[Category: Membrane]]
+[[Category: Novartis product nvp-blu040]]
+[[Category: Nucleotide-binding]]
+[[Category: Phosphoprotein]]
+[[Category: Polymorphism]]
+[[Category: Proto-oncogene]]
+[[Category: Sh2 domain]]
+[[Category: Small molecule inhibitor]]
+[[Category: Transferase]]
+[[Category: Tyrosine-protein kinase]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 28 10:45:42 2010''