User:Eric Martz/Sandbox 10: Difference between revisions
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==See Also== | ==See Also== | ||
* A detailed explanation and tutorial about [http://www2.uah.es/biomodel/en/model2/bilayer/inicio.htm Lipid Bilayers and the Gramicidin Channel]. | * A detailed explanation and tutorial about [http://www2.uah.es/biomodel/en/model2/bilayer/inicio.htm Lipid Bilayers and the Gramicidin Channel]. | ||
* [http://firstglance.jmol.org/fg.htm?mol=http://proteopedia.org/wiki/images/f/fd/Gramicidin_in_bilayer.pdb.gz This model in FirstGlance in Jmol]. | * [http://firstglance.jmol.org/fg.htm?mol=http://proteopedia.org/wiki/images/f/fd/Gramicidin_in_bilayer.pdb.gz This model in FirstGlance in Jmol]. Be sure to click the ''Ligands+'' and ''Water'' buttons! | ||
* [http://bme3d.molviz.org/ BioMolecular Explorer 3D], a resource for high school teachers that includes a section on gramicidin in a lipid bilayer. | |||
* [[High school teachers' resources]] | |||
==Notes== | ==Notes== | ||
Revision as of 05:00, 5 March 2010
Proposed Title: Gramicidin Channel in Lipid Bilayer
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Two copies of the gramicidin protein are shown here () arranged as they are believed to be when they form a channel through a lipid bilayer membrane[1]. The shape of the protein is shown transparent (ghostly), and a backbone trace connecting the alpha carbon atoms of each amino acid chain is opaque (solid).
- Show of the gramicidin protein chains.
- (Most hydrogen atoms are omitted.)
- Show . Notice how the hydrophobic lipid "tails" exclude water.
- Water passes .
- Show .
| Remember to use the popup button and then resize the popup window to enlarge the molecular scenes. |
See AlsoSee Also
- A detailed explanation and tutorial about Lipid Bilayers and the Gramicidin Channel.
- This model in FirstGlance in Jmol. Be sure to click the Ligands+ and Water buttons!
- BioMolecular Explorer 3D, a resource for high school teachers that includes a section on gramicidin in a lipid bilayer.
- High school teachers' resources
NotesNotes
- The PDB file shown here, File:Gramicidin in bilayer.pdb.gz, was kindly provided by Serge Crouzy.
ReferencesReferences
- ↑ Crouzy S, Woolf TB, Roux B. A molecular dynamics study of gating in dioxolane-linked gramicidin A channels. Biophys J. 1994 Oct;67(4):1370-86. PMID:7529578 doi:http://dx.doi.org/10.1016/S0006-3495(94)80618-6