3iut: Difference between revisions
No edit summary |
No edit summary |
||
Line 1: | Line 1: | ||
{{STRUCTURE_3iut| PDB=3iut | SCENE= }} | {{STRUCTURE_3iut| PDB=3iut | SCENE= }} | ||
===The Crystal Structure of Cruzain in Complex with a Tetrafluorophenoxymethyl Ketone Inhibitor=== | ===The Crystal Structure of Cruzain in Complex with a Tetrafluorophenoxymethyl Ketone Inhibitor=== | ||
{{ABSTRACT_PUBMED_20088534}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CYSP_TRYCR CYSP_TRYCR]] Hydrolyzes chromogenic peptides at the carboxyl Arg or Lys; requires at least one more amino acid, preferably Arg, Phe, Val or Leu, between the terminal Arg or Lys and the amino-blocking group. The cysteine protease may play an important role in the development and differentiation of the parasites at several stages of their life cycle. | |||
==About this Structure== | ==About this Structure== | ||
[[3iut]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IUT OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020088534</ref><references group="xtra"/><references/> | ||
[[Category: Cruzipain]] | [[Category: Cruzipain]] | ||
[[Category: Trypanosoma cruzi]] | [[Category: Trypanosoma cruzi]] | ||
Line 38: | Line 25: | ||
[[Category: Thiol protease]] | [[Category: Thiol protease]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||