Sandbox 5 Eric Martz: Difference between revisions

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This page displays an oligo-RNA containing a minimal decoding A site of the small subunit of the bacterial ribosome. The morph begins with an A site oligo-RNA (from [[3bnl]]) and shows it complexing with paromomycin, an aminoglycoside antibiotic that blocks translation (from [[1j7t]]).
This page displays an oligo-RNA containing a minimal decoding A site of the small subunit of the bacterial ribosome. The model without PAR is an oligo-RNA (from [[3bnl]]) which has cobalt hexammine (not shown) bound in its larger groove. The model with PAR is complexed to paromomycin, an aminoglycoside antibiotic (shown spacefilling) that blocks translation (from [[1j7t]]). The morph shows the transition between these two states.
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<applet load='Moran_asite_par_morph.pdb' size='400' frame='true' align='right' caption='Insert caption here'  
<applet load='Moran_asite_par_morph.pdb' size='400' frame='true' align='right' caption='Insert caption here'  

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Eric Martz