3l5c: Difference between revisions
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[[Image:3l5c.png|left|200px]] | |||
[[Image:3l5c. | |||
{{STRUCTURE_3l5c| PDB=3l5c | SCENE= }} | {{STRUCTURE_3l5c| PDB=3l5c | SCENE= }} | ||
===Structure of BACE Bound to SCH723871=== | ===Structure of BACE Bound to SCH723871=== | ||
{{ABSTRACT_PUBMED_20043696}} | {{ABSTRACT_PUBMED_20043696}} | ||
==About this Structure== | ==About this Structure== | ||
[[3l5c]] is a 2 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L5C OCA]. | |||
==See Also== | |||
*[[Beta secretase|Beta secretase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020043696</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
[[Category: Strickland, C.]] | [[Category: Strickland, C.]] | ||
[[Category: Zhu, Z.]] | [[Category: Zhu, Z.]] | ||
[[Category: Alzheimer]] | [[Category: Alzheimer]] | ||
[[Category: Aspartyl protease]] | [[Category: Aspartyl protease]] | ||
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[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Membrane]] | [[Category: Membrane]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 01:59, 26 July 2012
Structure of BACE Bound to SCH723871Structure of BACE Bound to SCH723871
Template:ABSTRACT PUBMED 20043696
About this StructureAbout this Structure
3l5c is a 2 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Zhu Z, Sun ZY, Ye Y, Voigt J, Strickland C, Smith EM, Cumming J, Wang L, Wong J, Wang YS, Wyss DF, Chen X, Kuvelkar R, Kennedy ME, Favreau L, Parker E, McKittrick BA, Stamford A, Czarniecki M, Greenlee W, Hunter JC. Discovery of Cyclic Acylguanidines as Highly Potent and Selective beta-Site Amyloid Cleaving Enzyme (BACE) Inhibitors: Part I-Inhibitor Design and Validation ( parallel) (1). J Med Chem. 2010 Feb 11;53(3):951-65. PMID:20043696 doi:10.1021/jm901408p