3l5c: Difference between revisions

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'''Unreleased structure'''
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[[Image:3l5c.jpg|left|200px]]


The entry 3l5c is ON HOLD
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{{STRUCTURE_3l5c|  PDB=3l5c |  SCENE=  }}


Authors: Strickland, C., Zhu, Z.
===Structure of BACE Bound to SCH723871===


Description: Structure of BACE Bound to SCH723871


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{{ABSTRACT_PUBMED_20043696}}
 
==About this Structure==
3L5C is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L5C OCA].
 
==Reference==
<ref group="xtra">PMID:20043696</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Strickland, C.]]
[[Category: Zhu, Z.]]
[[Category: Alternative splicing]]
[[Category: Alzheimer]]
[[Category: Aspartyl protease]]
[[Category: Bace1]]
[[Category: Disulfide bond]]
[[Category: Endoplasmic reticulum]]
[[Category: Endosome]]
[[Category: Glycoprotein]]
[[Category: Golgi apparatus]]
[[Category: Hydrolase]]
[[Category: Membrane]]
[[Category: Polymorphism]]
[[Category: Protease]]
[[Category: Transmembrane]]
[[Category: Zymogen]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 17 10:29:01 2010''

Revision as of 11:29, 17 February 2010

File:3l5c.jpg

Template:STRUCTURE 3l5c

Structure of BACE Bound to SCH723871Structure of BACE Bound to SCH723871

Template:ABSTRACT PUBMED 20043696

About this StructureAbout this Structure

3L5C is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Zhu Z, Sun ZY, Ye Y, Voigt J, Strickland C, Smith EM, Cumming J, Wang L, Wong J, Wang YS, Wyss DF, Chen X, Kuvelkar R, Kennedy ME, Favreau L, Parker E, McKittrick BA, Stamford A, Czarniecki M, Greenlee W, Hunter JC. Discovery of Cyclic Acylguanidines as Highly Potent and Selective beta-Site Amyloid Cleaving Enzyme (BACE) Inhibitors: Part I-Inhibitor Design and Validation ( parallel) (1). J Med Chem. 2010 Feb 11;53(3):951-65. PMID:20043696 doi:10.1021/jm901408p

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