3l5c: Difference between revisions
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{{STRUCTURE_3l5c| PDB=3l5c | SCENE= }} | |||
===Structure of BACE Bound to SCH723871=== | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | <!-- | ||
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{{ABSTRACT_PUBMED_20043696}} | |||
==About this Structure== | |||
3L5C is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L5C OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:20043696</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Memapsin 2]] | |||
[[Category: Strickland, C.]] | |||
[[Category: Zhu, Z.]] | |||
[[Category: Alternative splicing]] | |||
[[Category: Alzheimer]] | |||
[[Category: Aspartyl protease]] | |||
[[Category: Bace1]] | |||
[[Category: Disulfide bond]] | |||
[[Category: Endoplasmic reticulum]] | |||
[[Category: Endosome]] | |||
[[Category: Glycoprotein]] | |||
[[Category: Golgi apparatus]] | |||
[[Category: Hydrolase]] | |||
[[Category: Membrane]] | |||
[[Category: Polymorphism]] | |||
[[Category: Protease]] | |||
[[Category: Transmembrane]] | |||
[[Category: Zymogen]] | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 17 10:29:01 2010'' |
Revision as of 11:29, 17 February 2010
Structure of BACE Bound to SCH723871Structure of BACE Bound to SCH723871
Template:ABSTRACT PUBMED 20043696
About this StructureAbout this Structure
3L5C is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Zhu Z, Sun ZY, Ye Y, Voigt J, Strickland C, Smith EM, Cumming J, Wang L, Wong J, Wang YS, Wyss DF, Chen X, Kuvelkar R, Kennedy ME, Favreau L, Parker E, McKittrick BA, Stamford A, Czarniecki M, Greenlee W, Hunter JC. Discovery of Cyclic Acylguanidines as Highly Potent and Selective beta-Site Amyloid Cleaving Enzyme (BACE) Inhibitors: Part I-Inhibitor Design and Validation ( parallel) (1). J Med Chem. 2010 Feb 11;53(3):951-65. PMID:20043696 doi:10.1021/jm901408p
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