3kw9: Difference between revisions

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'''Unreleased structure'''
{{Seed}}
[[Image:3kw9.jpg|left|200px]]


The entry 3kw9 is ON HOLD until Paper Publication
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{{STRUCTURE_3kw9|  PDB=3kw9  |  SCENE=  }}


Authors: Uitdehaag, J.C.M., van Zeeland, M.
===X-ray structure of Cathepsin K covalently bound to a triazine ligand===


Description: X-ray structure of Cathepsin K covalently bound to a triazine ligand


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 13 13:32:56 2010''
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{{ABSTRACT_PUBMED_20149657}}
 
==About this Structure==
3KW9 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KW9 OCA].
 
==Reference==
<ref group="xtra">PMID:20149657</ref><references group="xtra"/>
[[Category: Cathepsin K]]
[[Category: Homo sapiens]]
[[Category: Uitdehaag, J C.M.]]
[[Category: Zeeland, M van.]]
[[Category: Cys protease]]
[[Category: Cysteine]]
[[Category: Disulfide bond]]
[[Category: Hydrolase]]
[[Category: Inhibitor]]
[[Category: Non-peptide]]
[[Category: Protease]]
[[Category: Thioimidate]]
[[Category: Thiol protease]]
[[Category: Zymogen]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar  3 16:36:44 2010''

Revision as of 17:36, 3 March 2010

File:3kw9.jpg

Template:STRUCTURE 3kw9

X-ray structure of Cathepsin K covalently bound to a triazine ligandX-ray structure of Cathepsin K covalently bound to a triazine ligand

Template:ABSTRACT PUBMED 20149657

About this StructureAbout this Structure

3KW9 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Rankovic Z, Cai J, Kerr J, Fradera X, Robinson J, Mistry A, Hamilton E, McGarry G, Andrews F, Caulfield W, Cumming I, Dempster M, Waller J, Scullion P, Martin I, Mitchell A, Long C, Baugh M, Westwood P, Kinghorn E, Bruin J, Hamilton W, Uitdehaag J, van Zeeland M, Potin D, Saniere L, Fouquet A, Chevallier F, Deronzier H, Dorleans C, Nicolai E. Design and optimization of a series of novel 2-cyano-pyrimidines as cathepsin K inhibitors. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1524-7. Epub 2010 Jan 25. PMID:20149657 doi:10.1016/j.bmcl.2010.01.100

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