3kai: Difference between revisions

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-{{Seed}}
-[[Image:3kai.png|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_3kai", creates the "Structure Box" on the page.
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-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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 {{STRUCTURE_3kai|  PDB=3kai  |  SCENE=  }}
 ===Structure-guided design of alpha-amino acid-derived Pin1 inhibitors===
+{{ABSTRACT_PUBMED_19969456}}
+==Function==
-<!--
+[[http://www.uniprot.org/uniprot/PIN1_HUMAN PIN1_HUMAN]] Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation.<ref>PMID:15664191</ref> <ref>PMID:16644721</ref> <ref>PMID:21497122</ref>
-The line below this paragraph, {{ABSTRACT_PUBMED_19969456}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 19969456 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_19969456}}
 ==About this Structure==
-KAI is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KAI OCA].
+[[3kai]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KAI OCA].
 ==Reference==
-<ref group="xtra">PMID:19969456</ref><references group="xtra"/>
+<ref group="xtra">PMID:019969456</ref><references group="xtra"/><references/>
 [[Category: Homo sapiens]]
 [[Category: Peptidylprolyl isomerase]]
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 [[Category: Sbdd]]
 [[Category: Small molecule]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan  6 09:04:55 2010''