3jsi: Difference between revisions
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[[Image:3jsi.png|left|200px]] | [[Image:3jsi.png|left|200px]] | ||
{{STRUCTURE_3jsi| PDB=3jsi | SCENE= }} | {{STRUCTURE_3jsi| PDB=3jsi | SCENE= }} | ||
===Human phosphodiesterase 9 in complex with inhibitor=== | ===Human phosphodiesterase 9 in complex with inhibitor=== | ||
{{ABSTRACT_PUBMED_19919087}} | {{ABSTRACT_PUBMED_19919087}} | ||
==About this Structure== | ==About this Structure== | ||
[[3jsi]] is a 2 chain structure of [[Phosphodiesterase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JSI OCA]. | |||
==See Also== | |||
*[[Phosphodiesterase|Phosphodiesterase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019919087</ref><references group="xtra"/> | ||
[[Category: 3',5'-cyclic-GMP phosphodiesterase]] | [[Category: 3',5'-cyclic-GMP phosphodiesterase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Liu, S.]] | [[Category: Liu, S.]] | ||
[[Category: Cgmp]] | [[Category: Cgmp]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
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[[Category: Phosphodiesterase]] | [[Category: Phosphodiesterase]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
Revision as of 05:02, 26 July 2012
Human phosphodiesterase 9 in complex with inhibitorHuman phosphodiesterase 9 in complex with inhibitor
Template:ABSTRACT PUBMED 19919087
About this StructureAbout this Structure
3jsi is a 2 chain structure of Phosphodiesterase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Verhoest PR, Proulx-Lafrance C, Corman M, Chenard L, Helal CJ, Hou X, Kleiman R, Liu S, Marr E, Menniti FS, Schmidt CJ, Vanase-Frawley M, Schmidt AW, Williams RD, Nelson FR, Fonseca KR, Liras S. Identification of a brain penetrant PDE9A inhibitor utilizing prospective design and chemical enablement as a rapid lead optimization strategy. J Med Chem. 2009 Dec 24;52(24):7946-9. PMID:19919087 doi:10.1021/jm9015334