3kl6: Difference between revisions
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===Discovery of Tetrahydropyrimidin-2(1H)-one derivative TAK-442: A potent, selective and orally active factor Xa inhibitor=== | ===Discovery of Tetrahydropyrimidin-2(1H)-one derivative TAK-442: A potent, selective and orally active factor Xa inhibitor=== | ||
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The line below this paragraph, {{ABSTRACT_PUBMED_20355714}}, adds the Publication Abstract to the page | |||
(as it appears on PubMed at http://www.pubmed.gov), where 20355714 is the PubMed ID number. | |||
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{{ABSTRACT_PUBMED_20355714}} | |||
==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
3KL6 is a 2 chains structure | 3KL6 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KL6 OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:20355714</ref><references group="xtra"/> | |||
[[Category: Coagulation factor Xa]] | [[Category: Coagulation factor Xa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Zymogen]] | [[Category: Zymogen]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu May 20 09:06:26 2010'' | ||
Revision as of 09:06, 20 May 2010
Discovery of Tetrahydropyrimidin-2(1H)-one derivative TAK-442: A potent, selective and orally active factor Xa inhibitorDiscovery of Tetrahydropyrimidin-2(1H)-one derivative TAK-442: A potent, selective and orally active factor Xa inhibitor
Template:ABSTRACT PUBMED 20355714
DiseaseDisease
Known disease associated with this structure: Factor X deficiency OMIM:[227600]
About this StructureAbout this Structure
3KL6 is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Fujimoto T, Imaeda Y, Konishi N, Hiroe K, Kawamura M, Textor GP, Aertgeerts K, Kubo K. Discovery of a tetrahydropyrimidin-2(1H)-one derivative (TAK-442) as a potent, selective, and orally active factor Xa inhibitor. J Med Chem. 2010 May 13;53(9):3517-31. PMID:20355714 doi:10.1021/jm901699j
Page seeded by OCA on Thu May 20 09:06:26 2010