3kb7: Difference between revisions

Revision as of 09:40, 20 May 2010

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File:3kb7.jpg

Template:STRUCTURE 3kb7

Crystal structure of Polo-like kinase 1 in complex with a pyrazoloquinazoline inhibitorCrystal structure of Polo-like kinase 1 in complex with a pyrazoloquinazoline inhibitor

Template:ABSTRACT PUBMED 20397705

About this StructureAbout this Structure

3KB7 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}

↑ Beria I, Ballinari D, Bertrand JA, Borghi D, Bossi RT, Brasca MG, Cappella P, Caruso M, Ceccarelli W, Ciavolella A, Cristiani C, Croci V, De Ponti A, Fachin G, Ferguson RD, Lansen J, Moll JK, Pesenti E, Posteri H, Perego R, Rocchetti M, Storici P, Volpi D, Valsasina B. Identification of 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivatives as a new class of orally and selective Polo-like kinase 1 inhibitors. J Med Chem. 2010 May 13;53(9):3532-51. PMID:20397705 doi:10.1021/jm901713n

Page seeded by OCA on Thu May 20 09:40:29 2010

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

[1] Beria I, Ballinari D, Bertrand JA, Borghi D, Bossi RT, Brasca MG, Cappella P, Caruso M, Ceccarelli W, Ciavolella A, Cristiani C, Croci V, De Ponti A, Fachin G, Ferguson RD, Lansen J, Moll JK, Pesenti E, Posteri H, Perego R, Rocchetti M, Storici P, Volpi D, Valsasina B. Identification of 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivatives as a new class of orally and selective Polo-like kinase 1 inhibitors. J Med Chem. 2010 May 13;53(9):3532-51. PMID:20397705 doi:10.1021/jm901713n

[xtra 1]

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-'''Unreleased structure'''
+{{Seed}}
+[[Image:3kb7.jpg|left|200px]]
-The entry 3kb7 is ON HOLD  until Paper Publication
+<!--
+The line below this paragraph, containing "STRUCTURE_3kb7", creates the "Structure Box" on the page.
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+or leave the SCENE parameter empty for the default display.
+-->
+{{STRUCTURE_3kb7|  PDB=3kb7  |  SCENE=  }}
-Authors: Bossi, R.T.
+===Crystal structure of Polo-like kinase 1 in complex with a pyrazoloquinazoline inhibitor===
-Description: Crystal structure of Polo-like kinase 1 in complex with a pyrazoloquinazoline inhibitor
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 18 18:52:36 2009''
+<!--
+The line below this paragraph, {{ABSTRACT_PUBMED_20397705}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 20397705 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_20397705}}
+==About this Structure==
+KB7 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KB7 OCA].
+==Reference==
+<ref group="xtra">PMID:20397705</ref><references group="xtra"/>
+[[Category: Homo sapiens]]
+[[Category: Polo kinase]]
+[[Category: Bertrand, J A.]]
+[[Category: Bossi, R T.]]
+[[Category: Atp-binding]]
+[[Category: Cell cycle]]
+[[Category: Cell division]]
+[[Category: Kinase]]
+[[Category: Mitosis]]
+[[Category: Nucleotide-binding]]
+[[Category: Nucleus]]
+[[Category: Phosphoprotein]]
+[[Category: Polymorphism]]
+[[Category: Protein kinase]]
+[[Category: Serine/threonine-protein kinase]]
+[[Category: Transferase]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu May 20 09:40:29 2010''