User:Anat Levit/Sandbox 2: Difference between revisions
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The phosphovariants can now be identified when the phosphorylation sites or interacting kinases were altered between subtype sequences. | The phosphovariants can now be identified when the phosphorylation sites or interacting kinases were altered between subtype sequences. | ||
The identified sites were classified according to one of the following types, defined by Ryu et al. 2009: | The identified sites were classified according to one of the following types, defined by Ryu et al. 2009: | ||
# In <scene name='User:Anat_Levit/ | # In <scene name='User:Anat_Levit/Sandbox_2/Type_i_variants/1' target='Phospho'>type I</scene> the phosphorylation site is in the same location as the variation, and can either create a new phosphorylation site (Type I+) or eliminate an existing site (Type I-) (<font color='green'>'''colored green'''</font>). | ||
# In <scene name='User:Anat_Levit/ | # In <scene name='User:Anat_Levit/Sandbox_2/Type_ii_variants/1' target='Phospho'>type II</scene> the variation is not in the same location as the phosphorylation site, and can either create a new phosphorylation site (Type II+) or eliminate an existing site (Type II-) (<font color='blue'>'''colored blue'''</font>). | ||
# <scene name='User:Anat_Levit/ | # <scene name='User:Anat_Levit/Sandbox_2/Type_iii_variants/1' target='Phospho'>Type III</scene> are variations that change only the type of kinase involved, without affecting the phosphorylation site itself (<font color='red'>'''colored red'''</font>). | ||
<scene name='User:Anat_Levit/ | <scene name='User:Anat_Levit/Sandbox_2/Type_iii_variants/2' target='Phospho'>Identical</scene> phosphor-acceptor residues predicted to be phosphorylated by the same kinases are <font color='yellow'>'''colored yellow'''</font> (<scene name='User:Anat_Levit/Sandbox_1/All_phosphosites/1' target='Phospho'>view all predictions</scene>). | ||