User:Anat Levit/Sandbox 1: Difference between revisions
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<scene name='User:Anat_Levit/Sandbox_1/Type_i/3'>Identical</scene> phosphor-acceptor residues predicted to be phosphorylated by the same kinases are <font color='yellow'>'''colored yellow'''</font> (<scene name='User:Anat_Levit/Sandbox_1/All_phosphosites/1'>view all predictions</scene>). | <scene name='User:Anat_Levit/Sandbox_1/Type_i/3'>Identical</scene> phosphor-acceptor residues predicted to be phosphorylated by the same kinases are <font color='yellow'>'''colored yellow'''</font> (<scene name='User:Anat_Levit/Sandbox_1/All_phosphosites/1'>view all predictions</scene>). | ||
As seen from the results, homologues residues in the receptors are predicted to be phosphorylated by different kinases, and some of the predicted phospho-sites are receptor unique. | |||
By understanding the flexible nature of PK receptors phosphorylation it may be possible to develop agonists or allosteric modulators that promote a subset of phosphorylation events on the target GPCR and thereby restrict the action of the drug to a particular receptor mediated signalling response. | |||
== Binding site analysis == | == Binding site analysis == | ||