3ird: Difference between revisions

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[[Image:3ird.jpg|left|200px]]


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==Structure of dihydrodipicolinate synthase from Clostridium botulinum==
The line below this paragraph, containing "STRUCTURE_3ird", creates the "Structure Box" on the page.
<StructureSection load='3ird' size='340' side='right'caption='[[3ird]], [[Resolution|resolution]] 2.23&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3ird]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_botulinum_A_str._Hall Clostridium botulinum A str. Hall]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3bi8 3bi8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IRD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IRD FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.23&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLT:D-MALATE'>MLT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
{{STRUCTURE_3ird| PDB=3ird |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ird FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ird OCA], [https://pdbe.org/3ird PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ird RCSB], [https://www.ebi.ac.uk/pdbsum/3ird PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ird ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A5I6N2_CLOBH A5I6N2_CLOBH] Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).[HAMAP-Rule:MF_00418][SAAS:SAAS00021616]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ir/3ird_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ird ConSurf].
<div style="clear:both"></div>


===Structure of dihydrodipicolinate synthase from Clostridium botulinum===
==See Also==
 
*[[Dihydrodipicolinate synthase|Dihydrodipicolinate synthase]]
 
__TOC__
==About this Structure==
</StructureSection>
3IRD is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Clostridium_botulinum_a_str._hall Clostridium botulinum a str. hall]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3bi8 3bi8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IRD OCA].
[[Category: Clostridium botulinum A str. Hall]]
[[Category: Clostridium botulinum a str. hall]]
[[Category: Large Structures]]
[[Category: Dihydrodipicolinate synthase]]
[[Category: Atkinson S]]
[[Category: Atkinson, S.]]
[[Category: Dobson RCJ]]
[[Category: Dobson, R C.J.]]
[[Category: Perugini MA]]
[[Category: Perugini, M A.]]
[[Category: Amino-acid biosynthesis]]
[[Category: Clostridium botulinum]]
[[Category: Cytoplasm]]
[[Category: Diaminopimelate biosynthesis]]
[[Category: Dihydrodipicolinate synthase]]
[[Category: Lyase]]
[[Category: Lysine biosynthesis]]
[[Category: Schiff base]]
 
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