C-di-GMP: Difference between revisions

Latest revision as of 23:45, 8 January 2012

cyclic di-GMP, as found in complex with the diguanylate cyclase PleD 2v0n

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Cyclic di-GMP, (bis-(3'-5') cyclic diguanylic acid)

C-di-GMP is a second messenger that mediates the regulation of cell-surface associated traits in bacteria.

is a cyclic dinucleotide with a 12-membered macro-cycle composed of the the phosphate and ribose moieties. It tends to associate to form with intercalated, stacked bases.

Several protein structures involved in c-di-GMP signaling have been determined (see C-di-GMP signaling).

UNIPROT link

ReferencesReferences

Reviews: ^{[xtra 1]}^{[xtra 2]}

↑ Egli M, Gessner RV, Williams LD, Quigley GJ, van der Marel GA, van Boom JH, Rich A, Frederick CA. Atomic-resolution structure of the cellulose synthase regulator cyclic diguanylic acid. Proc Natl Acad Sci U S A. 1990 Apr;87(8):3235-9. PMID:2158107
↑ Guan Y, Gao YG, Liaw YC, Robinson H, Wang AH. Molecular structure of cyclic diguanylic acid at 1 A resolution of two crystal forms: self-association, interactions with metal ion/planar dyes and modeling studies. J Biomol Struct Dyn. 1993 Oct;11(2):253-76. PMID:8286055

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Tilman Schirmer

[1] Egli M, Gessner RV, Williams LD, Quigley GJ, van der Marel GA, van Boom JH, Rich A, Frederick CA. Atomic-resolution structure of the cellulose synthase regulator cyclic diguanylic acid. Proc Natl Acad Sci U S A. 1990 Apr;87(8):3235-9. PMID:2158107

[2] Guan Y, Gao YG, Liaw YC, Robinson H, Wang AH. Molecular structure of cyclic diguanylic acid at 1 A resolution of two crystal forms: self-association, interactions with metal ion/planar dyes and modeling studies. J Biomol Struct Dyn. 1993 Oct;11(2):253-76. PMID:8286055

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[xtra 2]

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-Cyclic di-GMP, (bis-(3'-5') cyclic diguanylic acid)
+<applet load='2v0n' scene='C-di-GMP/C-di-gmp/1' size='400' frame='true' align='right' caption='cyclic di-GMP, as found in complex with the diguanylate cyclase PleD  [[2v0n]]' />
+Cyclic di-GMP, (bis-(3'-5') cyclic diguanylic acid)<br><br>
+C-di-GMP is a second messenger that mediates the regulation of cell-surface associated traits in bacteria.
+<scene name='C-di-GMP/C-di-gmp/3'>C-di-GMP</scene>
+is a cyclic dinucleotide with a 12-membered macro-cycle composed of the the phosphate and ribose moieties.  It tends to associate to form  <scene name='C-di-GMP/C-di-gmp/4'>dimers</scene> with intercalated, stacked bases.
+Several protein structures involved in c-di-GMP signaling have been determined (see  [[C-di-GMP signaling]]).
+<br><br>
 [http://www.uniprot.org/keywords/973 UNIPROT link]
+<br><br><br><br><br><br><br><br>
+<br><br>
-<applet load='2v0n' scene='User:Tilman_Schirmer/Sandbox_213/C-di-gmp_dimer/1' size='400' frame='true' align='right' caption=cyclic di-GMP' />
+==References==
+Reviews:
+<ref group="xtra">PMID:2158107</ref><ref group="xtra">PMID: 8286055 </ref>
+<references group="xtra"/>
-<scene name='User:Tilman_Schirmer/Sandbox_213/C-di-gmp_dimer/1'>C-di-GMP</scene>
+[[Category: C-di-GMP]]
-is a cyclic dinucleotide with a 12-membered macro-cycle composed of the the phosphate and ribose moieties.

C-di-GMP: Difference between revisions

Latest revision as of 23:45, 8 January 2012

ReferencesReferences

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