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'''2009 H1N1 swine flu genome and protein analysis'''
'''2009 H1N1 swine flu genome and protein analysis'''


This page was created by Michael Strong, other contributers include ...
[[User:Michael_Strong|home]] <font color="blue">•</font>  [[User:Michael_Strong/H1N1|H1N1]] <font color="blue">•</font>  [[User:Michael_Strong/H1N1/PB2|PB2]]<font color="blue">•</font> [[User:Michael_Strong/H1N1/PB1|PB1]]<font color="blue">•</font>  [[User:Michael_Strong/H1N1/PA|PA]]  <font color="blue">•</font> [[User:Michael_Strong/H1N1/HA|HA]] <font color="blue">•</font>  [[User:Michael_Strong/H1N1/NP|NP]] <font color="blue">•</font>  [[User:Michael_Strong/H1N1/NA|NA]] <font color="blue">•</font>  [[User:Michael_Strong/H1N1/MP|MP]] <font color="blue">•</font>  [[User:Michael_Strong/H1N1/NS|NS]]


[[User:Michael_Strong|home]] <font color="blue">•</font>  [[User:Michael_Strong/H1N1|H1N1]] <font color="blue">•</font>  [[User:Michael_Strong/H1N1/PB2|PB2]]<font color="blue">•</font> [[User:Michael_Strong/H1N1/PB1|PB1]]<font color="blue">•</font>  [[User:Michael_Strong/H1N1/PA|PA]]  <font color="blue">•</font> [[User:Michael_Strong/H1N1/HA|HA]] <font color="blue">•</font>  [[User:Michael_Strong/H1N1/NP|NP]] <font color="blue">•</font>  [[User:Michael_Strong/H1N1/NA|NA]] <font color="blue">•</font>  [[User:Michael_Strong/H1N1/MP|MP]] <font color="blue">•</font>  [[User:Michael_Strong/H1N1/NS|NS]]


Shown below are Protein Structural Homology Models of the PB2, PA, HA, NP, NA, MP1, MP2, NS1 and NS2 proteins from the 2009 Mexico [http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=643780 A/Mexico/InDRE4487/2009] H1N1 Swine flu genome.  Sequence polymorphisms of the PB2, PB1, PA, HA, NP, NA, MP1, MP2, NS1 and NS2 proteins are also indicated, as identified by comparison of subsequently sequenced 2009 H1N1 strains from around the globe.  The "green links" next to the listed amino acids highlight the amino acid polymorphisms in the structural homology models. More detail on each protein, including Multiple Sequence Alignments of newly sequence H1N1 strains, Sequence Polymorphisms, and Related Sequence Homologs are provided on the individual protein pages (links above). 
Genome and protein sequences obtained from: http://www.ncbi.nlm.nih.gov/genomes/FLU/SwineFlu.html. Multiple sequence alignments of the PB2, PB1, PA, HA, NP, NA, MP, and NS proteins from 2009 H1N1 strains from Mexico, California, Texas, New York, and Canada are also provided below. 


Shown below are Clustal Multiple Sequence Alignmnents of the Protein Sequences from five strains of the recent 2009 H1N1 Swine Influenza Virus, including isolates from Mexico, California, Texas, New York, and Canada.  Protein sequences obtained from: http://www.ncbi.nlm.nih.gov/genomes/FLU/SwineFlu.html. Multiple sequence alignments of the PB2, PB1, PA, HA, NP, NA, MP, and NS proteins are provided.
== PB2 Protein Structural Homolgy Model ==
== PB2 Protein Structural Homolgy Model ==


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